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Explain the etiology and genetics of disease phenylketonuria (PKU) Phenylketonuria (PKU) refers to a disease found within humans in which the affected individual does not have enzyme phenylalanine hydroxylase. This enzyme is required in order to metabolize the amino acid phenylalanine to tyrosine. When left untreated phenylalanine will be transformed to phenylketone and accumulates within the body leading to the brain development disorders, mental retardation and seizures. Assume two normal adults have one child who has trait and a second child who is normal.
a) Is PKU inherited as the dominant or recessive trait?
b) Describe how you came to this conclusion
c) Explain the genotypes of the each of the parents?
d) Explain the genotype of child with PKU?
Across between short-tailed mouse and a long-tailed mouse yields all short-tailed mice. Crosses among the F1 yield an F2 of 48 short-tailed and 22 long-tailed. Suggest the model to explain and perform a chi-square test of your results.
Distribute one cup with sugar water and one with fresh water. Take a sip of the sugar water and swish it around in your mouth for several seconds without swallowing it; gradually, it has to tasteless sweet. After swallowing it (or spitting it back in..
Most of us can't even imagine a world without oxygen. Though, as you learned earlier, chemically oxygen is a powerful oxidizing compound. What effect(s) would the increase in oxygen levels of atmosphere have on the organisms that existed at that time..
Animals obtain energy throughout a series of chemicals reactions in which sugar (C6 H12 O6) and oxygen gas (O2) are reactant. This produces water (H2O) and carbon dioxide (CO2) as waste products. How might you use a radioactive isotope to find out wh..
Using this information, what two strategies can you use to isolate the giraffe's gene from its genomic library. If only females are found to be black, what were genotypes of the parents.
Since a doughnut contains a large quantity of energy that can become available for our metabolism when eaten, why isn't the doughnut "jumping" all over the counter or hot to the touch.
What blood test would be performed before starting the transfusion. Calcium levels in blodd are dropping to dangerously low levels. The hormone PTH is released and almost immediately calcium levels begin to rise. Shortly after, PTH release slows. Is ..
Which characteristic of cell membranes might explain why fat-soluble substances such as chloroform and ether rapidly affect cells.
How does the increase in estrogen level correspond to the thickness of uterine lining (endometrium)? Clarify why this makes sense based on the function of estrogen.
What would your expected results be (growth or no growth) if you transformed bacteria with a plasmid that had ampicillin and kanamynic (another antibiotic) resistance and plated them. Situation growth or no growth and explain your reply.
The results of these experiments point to that plants can be genetically transformed for resistance to virus disease development. What is an expected outcome of a cross between a homozygous recessive woman and a man with hypophosphatemia.
In metabolic processes of cell respiration and photosynthesis, prosthetic groups as in heme and iron-sulfur complexes are encountered. What do they do.
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