Malonic ester synthesis Assignment Help

Assignment Help: >> Chemical Reactions - Malonic ester synthesis

The malonic ester synthesis is an organic reaction where diethyl malonate or other ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then changed to a substituted acetic acid. The main drawback of malonic ester synthesis is that the alkylation stage can also give dialkylated structures. This makes separation of products hard and yields lesser.

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