The Japp-Maitland condensation is a chemical reaction and a kind of Aldol reaction and a tandem reaction. In a reaction between the ketone 2-pentanone and the aldehyde benzaldehyde catalyzed by base the bis Aldol adduct is produced first. The second step is a ring-closing reaction when one hydroxyl group shifts the other in a nucleophilic substitution giving a oxo-tetrahydropyran.
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