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Uric acid is the main nitrogenous waste product of uricotelic organisms (birds, insects and reptiles), but is also established in ureotelic organisms from the breakdown of the purine bases from RNA and DNA. Some individuals have a high serum level of sodium urate (the predominant form of uric acid at neutral pH) that can lead to crystals of this compound being deposited in the joints and kidneys and a condition known as gout, a part of arthritis characterized by extremely painful joints.
Figure: Uric acid.
Where in eukaryotic cells does mRNA synthesis occur? To where do these molecules migrate?
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