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The nucleus has an inner and an outer membrane and is perforated through 3000-4000 nuclear pores. Each pore having of a nuclear pore complex of more than 100 several proteins organized in a hexagonal array. Whereas little molecules can pass by the pore by free diffusion and large proteins entering the nucleus need a nuclear localization signal. That is four to eight amino acids long and is rich in the positively charged amino acids arginine and lysine as well as commonly having proline, and is situated internally within the polypeptide chain. The protein is taken by the pore in an ATP- requires step and enters the nucleus without cleavage of the localization signal.
Figure: Uptake of proteins into the mitochondrial matrix
Explain about the Cancer and Infertility - Obesity? Cancer: Risk of cancers of the colon, rectum and prostrate increases greatly in obese men while obese women are more likely
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How do the cheek and onion cells visually resemble one another, and why are shapes of squamous cells so different than the onion cells?
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