Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
Why are the tropical forests also known as stratified forests? In the tropical forests tall trees of several species have their crowns forming a superior layer under which dive
Congenital Discrete Subvalver Stenosis : The abstraction could be fibrous or fibro muscular. It could be anywhere from just below the aortic cusps upto the level of the free edge
What similarities do birds and reptiles share regarding external coverage, reproduction and excretion? Regarding external coverage, birds are same to reptiles as they present
Determine the Causal factors of nervous system Although, the brain and spinal cord are surrounded by tough membranes, enclosed in the bones of the skull and spinal vertebrae, a
Q. Fluoxetine is an antidepressant drug that presents an action mechanism related to the synaptic transmission. What is that mechanism? Fluoxetine is a substance that inhibits
Ecology Very often a word has a precise well-defined meaning in scientific literature but is loosely used in everyday language. It is, therefore, necessary for you to be clear
Define endocytosis of GLUT4 Transporters Person X is a healthy human who has volunteered to take experimental drug Y. Person X has a normal dinner at 6 PM on April 1 and then
Consistently overwatering a potted tomato pla nt will eventually kill it. Using the map, suggest why waterlogged soil results in plant death. O2 cannot reach respiring root cells.
Q. During mitotic anaphase is there separation of identical chromatids or separation of homologous chromosomes? In the anaphase of mitosis the identical chromatids complete and
What are the typical vegetation and the typical fauna of the taigas? Taiga, or the boreal forest, is characterized by coniferous trees, pine forests. There are also mosses, lic
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd