Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
what are the function of nucleus
Left Antero Lateral Thoracotomy Approach : Arterial and central venous pressure monitoring lines are placed. A left antero lateral thoracotomy is done through the 5th or 4th
Define about the Resistant Starch? Until 1980's starch was thought to be completely hydrolyzed and absorbed from the small intestine of man, independent of its source, type and
Following a meal, fructose 2,6 bisphosphate levels will be elevated in the liver. Under these metabolic conditions, all of the following enzymes will be active except: -PFK1
How are the plant tissues classified according to their functions? Plant tissues are separated into growth (embryonic) tissues, supporting, filling and photosynthetic tissues (
What does acute disease mean? An sharp disease is which does not last for a longer duration n has no weakness in the body
The interior of the right atrium has a rough anterior part, the atrium proper and a smooth part called the sinus venarum. Also it has an appendage called the auricle. All the large
Define Methods of Estimation of Energy Expenditure and Requirements? There are a variety of methods available to measure human energy expenditure. Knowledge of these methods wi
Question 1 Write a short note on the following- Theory of clonal selection Interferons Super antigens Helper T cells Auto immunity Active Immunization
What are the typical components of a closed circulatory system? The typical components of the closed circulatory system are the blood vessels within which blood circulates (vei
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd