Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
Which of the following are true for ventilation? A. The problems with ventilation induced by injection of curare occur because of the drug's direct action on nicotinic ACh Rec
Define Hypoglycemic effects of Dietary Factor with antinutritional effect? Of the different carbohydrate foods tested for starch digestibility and blood glucose response, those
wine turns sour beause of the action of which bacteria? aerobic or anerobic?
Determine about the Manganese Manganese performs some functions in photosynthesis and acts to regulate the intake of certain elements and their oxidation states. Several cr
Explain Difficult Feeding and Poor Growth to recognition of congenital heart disease? Difficult Feeding and Poor Growth: The parent of an infant with CHD may complain that the
Give an introduction to intensive care ? Intensive Care Medicine has its origins from the polio epidemic of 1952 in Copenhagen. Patients who suffered respiratory paralysis were
Q. Why doesn't the food enter the trachea instead of going to the esophagus? When food is swallowed the swallow reflex is activated and the larynx closes and elevates to avoid
Explain the major classes of lipids The major classes of lipids are simple lipids (acylglycerols and waxes); Compound lipids (glycerophospholipids); Derived lipids (compounds t
What are all possibilities of genotypes and phenotypes formed in the combination of alleles responsible for the production of factor VIII? Considering the alleles X and Xh, whe
Anticonvulsants and Cerebral Palsy Anticonvulsants : drugs that prevent reduce or stop convulsions or seizures. Cerebral Palsy: A group of chronic foundations affecting
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd