Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
Q. Explain the types of classification of plants? It is practically impossible for anyone to study all the plants of the world, 'even if one spends whole life. Thus, it is nece
What happens when the cell membrane or plasma membrane ruptures or breaks down? When cell membrane ruptures Ions leek out and if not repaired in time the cell will die. As we k
Consider 100 ml of 10% solute and 10 ml of 50& solute. Which has the greatest concentration of solute? What is the concentration of solute? Which has a greater quantity of solute?
Q. Living beings are made of inorganic and organic substances. According to the molecular complexity how can each of those substances be classified? Inorganic substances, mole
Q. What is the name of the cytoplasm division in the end of mitosis and what are the differences in this process between animal and plant cells? Cytoplasm division occurs afte
What is the stage of cellular respiration during which carbon dioxide is liberated? In aerobic cellular respiration the release of carbon dioxide occurs in the transformation o
Protein of Animal Origin - Meat Meat: Skeletal or striated muscles are used for food purposes. Flesh of cattle, sheep and swine comprise most of the meat contents. Edible mea
Hard paste removal - Hard setting Ca(Ho) 2 paste (like Endocal 10) can be softened by EDTA and removed by file or microdebrider. - Care must be taken not to gouge or
what is the biological significance of the skeleton and supporting system in animals
Organisms of the so-called HACEK group, (Haemophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella species, Kingella kingae) which are part of the upper
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd