Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
What is the most abundant form under which nitrogen is found in nature? The most abundant nitrogen-containing molecule found in nature is molecular nitrogen (N2). The air is 80
What is the external rigid carapace of arthropods called? Of which substance is it made? Which type of organic molecule is that substance? The external carapace of arthropods i
Tr aumatic reticuloperitonitis (TRP) It is also known as traumatic gastritis, hardware disease or traumatic reticulitis. Et i o l o g y : Frequentl
identify 7 speccific ways in which you can diversify carbon-containing compounds
Q Where in the cell can ribosomes be found? What is the major biological function of ribosomes? Ribosomes can be found free in the cytoplasm, adhered to the external side of th
What are the Results of Chronic Pulmonary Thromboembolism? Results : The reported mortality is between 5 and 24 per cent. On follow-up, the six-year survival in the best ce
What is the logic of the transfusional compatibility concerning the Rh blood group system? The Rh + donor can only donate blood to the Rh + recipient. The person that lacks t
Which of the below terms describes study of animal behavior based on comparisons, observation of patterns, and consideration of environmental adaptations? Is it: a) Ethology (p
Question 1 Explain various methods employed for the lab diagnosis of rabies Definition of rabies Listing of various methods employed for rabies Explaining the meth
Q. What is Galactosemia? Galactosemia is a genetic disorder caused by deficient functioning of any of these three enzymes namely galactokinase, galactose -1 - phosphate uridyl
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd