Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Q. What is low - density lipoprotein receptor pathway?
Ans.
The increasing cellular free cholesterol generated regulates the activities of two enzymes that are of crucial importance in cholesterol homeostasis. HMG-CoA reductase (the major rate-determining enzyme in the cholesterol synthetic pathway) is inhibited, reducing cholesterol synthesis. Acyl CoA: cholesterol acyl transferase (ACAT) is activated, thus facilitating the re-esterification of cholesterol to cholesterol ester.
Thus the LDL receptor pathway is a closely integrated system by which cells acquire cholesterol and cellular cholesterol homeostasis is maintained. The therapeutic potential of interrupting this pathway will become apparent when the statin drugs which are inhibitors of HMG-CoA reductase are discussed.
It is the activity of LDL receptors in the liver that largely controls plasma LDL levels. Approximately 70 per cent of LDL is removed by this pathway.
What are some human diseases caused by virus and what are their respective modes of transmission? The main viral diseases transmitted by respiratory secretions (cough, sneezes)
Amino acid is any of a class of 20 molecules which are combined to form the proteins in living things. Consisting of the general formula NH2-CHR-COOH, where "R" is the side chain
Classification of Multicellular Animals - Coelom We know earlier that the pseudocoel gave animals specific selective benefits. Among other things, this fluid-tilled space wor
Who was Charles Darwin? The Charles Darwin was an English naturalist born in 1809 and considered the father of the theory of evolution. By the end of the year 1831, before turn
C h oice of transgenic animal First and foremost is the selection of animal species in which gene of interest is to be transferred. Whatever is the goal of production of tran
What is nidation? In which phase of the menstrual cycle does nidation occur? Nidation is the implantantion of the embryo in the uterus. Nidation happens around the 7th day afte
DIFFERENT PHASES OF SPERMATOGENESIS Spermatogenesis complete into two phases. 1 . Spermatocytogenesis The entire process can be divided into three phases : (i
The dynamic response of the building to earthquake ground motion is the most important cause of damages to the building that are induced by earthquake. Failure of the ground and so
Q. Which is the cell organelle that is specializing in aerobic respiration? The mitochondria are cell organelles that are specialized in aerobic respiration. Q. Of which ma
Age-Sex Distribution While studying exponential growth we need to know more than just the birth and death rates because these rates vary with age and sex. Age structure in a
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd