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Histone methyl transferases (HMTs) having a protein domain called SET. This domain is responsible to adding methyl groups to histones. Which of the following is a false statement regarding the methylation of histones?
A. Methyl groups are added mostly at lysine (K) and arginine (R) amino acids within histones.
B. Dissimilar HMT proteins very in their substrate specificity and in the number of methyl groups that can be added to amino acids within histone proteins.
C. The addition of methyl groups generally will enhance the hydrophobicity of histones thereby causing them to package DNA more tightly.
D. Methylation enhances the positive charge on histone proteins thereby resulting in a more condensed chromosome.
supernatentmeans what
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