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Types of Leukemia
Leukaemia may be chronic or acute and is classified into the following categories:
i) Acute Lymphocytic Leukaemia (ALL)
This is the most common form of children leukaemia and accounts for about 80 per cent of childhood leukaemias. In this type of disease lymphoid cell line is affected. The ALL can be sub-classified on the basis of cellular characteristics related to thymic (T cell) and bursal-equivalent (B cell) origin of normal lymphocytes.
ii) Acute Non-lymphocpic Leukaemia (ANLL)
This is a group of malignant disease in which the basic abnormality is a generalised progressive proliferation of mature monocytes and myelocytes fiom the bone marrow that invade the blood and other tissue. These include acute myeloblastic or myelocytic Leukemia (AML), acute promyelocytic leukemia (APML), acute monocytic leukemia Hamafologiul Disorders (AMML) and acute monocytic leukemia.
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Question 1: Mention the types of IRBs. If the IRB disapproves clinical study, can the sponsor approach another IRB? Justify your answer. Mention different types of IRBs
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