Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Explain assessment of iron status - serum ferritin, Explain assessment of i...

Explain assessment of iron status - Serum Ferritin? Serum Ferritin: This method is indicative of iron stores. As we know, a long term negative iron balance first results in dep

Show Relation between tissue and the implant material, Relation between Tis...

Relation between Tissue and the implant material The biologic interaction between the tissue and the implant material at an  interface may result in a variety of phenomena such

What are the corals, Q What are the corals? Corals are characterized by...

Q What are the corals? Corals are characterized by their polypoid shape, slow growth and sessility and secretion of a solid skeleton made of calcium carbonate. Numerous coral i

Essentials of Human Diseases and Conditions, How do pathological conditions...

How do pathological conditions affect homeostasis of your body?

Measurement of functional property of fats and oil, Measurement of Function...

Measurement of Functional Property of fats and oil Fats and oils have several functional properties that affect the quality of processed foods. In deep fat frying, the roles p

Mycoplasmosis-contagious bovine pleuropneumonia (cbpp), Contagious bovine p...

Contagious bovine pleuropneumonia (CBPP) This is a highly fatal disease of cattle and of major economic importance in certain tropical countries. It also affects buffaloes, bi

Define characteristic of doppler echocardiographic, Q. Define characteristi...

Q. Define characteristic of Doppler Echocardiographic? Ans. Doppler findings of cardiac tarnponade are based on the following characteristic respiratory variations in intr

Coelenterata, is cnidaria having both interacellular & extracellular digest...

is cnidaria having both interacellular & extracellular digestion?

Differentiating causes of hypoxemia, Study and complete the following Mini ...

Study and complete the following Mini Clini: Differentiating Causes of Hypoxemia. Explain the pathophysiological mechanism of how the following disorders cause hypoxia: Pleu

What is homogenization, What is homogenization Emulsions may also be st...

What is homogenization Emulsions may also be stabilized by a process known as homogenization, in which the size of the dispersed fat globules is greatly reduced to more or less

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd