Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Define role in glucose, Define Role in Glucose, Lipid and Nucleic Acid Meta...

Define Role in Glucose, Lipid and Nucleic Acid Metabolism? Chromium leads to a decrease in blood glucose concentration in people with elevated glucose levels and an increase in

Explain about the dehydration, Explain about the Dehydration? Dehydrati...

Explain about the Dehydration? Dehydration is defined as the excessive loss of body water. It may occur because of inadequate intake, or abnormal loss of body water or a combin

Blood flow during exercise - circulation, Normal 0 false fals...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Discovery of the cell, Q. Describe the Discovery of the Cell? Ans: The ...

Q. Describe the Discovery of the Cell? Ans: The discovery that living organisms are composed of cells was made by an Englishman, Robert Hooke, in 1665. Hooke used the light mic

What are the classification of diabetes, Q. What are the Classification of ...

Q. What are the Classification of Diabetes? Several forms of diabetes have been identified as a result of research and survey conducted world-wide. These forms of diabetes incl

Fixation and movement to echinoderms, Q What is the system that permits fix...

Q What is the system that permits fixation and movement to echinoderms? The system that permits fixation and movement to substrates in echinoderms is called the ambulacral syst

HEALTHY DIET, EXPLAIN THE CONSTITUENT OF FOOD GROUPS AND THEIR SOURCES

EXPLAIN THE CONSTITUENT OF FOOD GROUPS AND THEIR SOURCES

Explain the anatomic variability of long buccal nerve, Anatomic variability...

Anatomic variability of long buccal nerve demands caution during surgery. Discuss Long buccal nerve, a branch of the mandibular division of trigeminal nerve emerges deep to the

Explain the superficial minor burns, Explain the Superficial Minor Burns? ...

Explain the Superficial Minor Burns? Superficial minor bums are immersed immediately in cool water if possible. The burn is carefully cleaned to prevent infection. If dirt is d

Explain objective anti-arrhythmic pacemaker defibrillators, Explain Objecti...

Explain Objective Anti-arrhythmic pacemaker defibrillators? After reading this unit, you should be able to: 1 describes the classification of ant arrhythmic drugs; 2 understand

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd