Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Common eye defects, COMMO N EYE DEFECTS - 1 .       Glaucoma - Pres...

COMMO N EYE DEFECTS - 1 .       Glaucoma - Pressure of aquous humour is increased, retina is degenerated. 2 .       Presbyopia - Due to non etastic cilliary muscles,

Can you explain antibiotics, Q. Can you explain Antibiotics? The antibi...

Q. Can you explain Antibiotics? The antibiotics are the chemicals produced by microorganisms which are able to destroy or inhibit the growth of other microorganisms. The therap

Viruses.., are there non-parasitic viruses

are there non-parasitic viruses

Typical conformation of the age pyramids, Q. What is the typical conformati...

Q. What is the typical conformation of the age pyramids of underdeveloped countries? The age pyramids of the peripheral countries or the underdeveloped countries have character

Define types of dryers, Define types of Dryers? There are many other dr...

Define types of Dryers? There are many other dryer types available, such as; Osmotic Drying Impingement Drying Microwave and Dielectric Drying Superheated

What is the kind of nitrogen waste that mammals eliminate, Q What is the ki...

Q What is the kind of nitrogen waste that mammals eliminate? Like chondrichtian fishes and adult amphibians, mammals are ureotelic that is they excrete urea. Q. How do plac

Which is the normal sign of the electric charge, Which is the normal sign o...

Which is the normal sign of the electric charge among the two sides of the neuron plasma membrane? What is the potential difference (voltage) generated among these two sides? What

Pleuritis, P l e u r iti s It is the acute or chronic inflammatio...

P l e u r iti s It is the acute or chronic inflammation of the pleural membranes. It is characterized by pain during respiration, pleural effusion, and shallow rapid resp

Skeletons of radiolarians, Skeletons of radiolarians The skeletons of ...

Skeletons of radiolarians The skeletons of radiolarians and foraminiferans form a primary constituent of ocean bottoms where they form 30% or more of the sediment. It is calle

Name mimicry by which insect mimics insec for protection, From the followin...

From the following, name the type of mimicry by which a palatable, acceptable insect mimics an unfavorable, noxious insec for protection. a) Batesian mimicry (pron: BATE-see-an

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd