Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

What is the etiological agent of cutaneous leishmaniasis, Q. What is the et...

Q. What is the etiological agent of cutaneous leishmaniasis? How is the disease transmitted and what are its typical manifestations? The protozoan Leishmania braziliensis is et

Define the theory or principle of drying, Define the Theory or Principle of...

Define the Theory or Principle of Drying? Drying can be illustrated as the application of heat under controlled conditions to eliminate the majority of the water generally avai

Which amino acid can form disulfide bonds, a. Which amino acid can form dis...

a. Which amino acid can form disulfide bonds? b. Which level of protein structure do disulfide bonds affect? How? c. Cytoplasmic proteins rarely form disulfide bonds, even if they

Signs and symptoms of hypoglycaemia, Q. Signs and Symptoms of Hypoglycaemia...

Q. Signs and Symptoms of Hypoglycaemia? Let us now learn about signs and symptoms of hypoglycaemia. It is important for you know these because you can help the patient and fami

Manufacture of metallurgical coke, Using high temperature carbonization, me...

Using high temperature carbonization, metallurgical coke  (hard coke) can be prepared by two processes. 1.      Beehive coke oven process. 2.      Otto-hoffmann's by-product

Aeration, Aeration A well-aerated soil is one in which gases are availa...

Aeration A well-aerated soil is one in which gases are available to plant roots and other soil organisms, in sufficient quantities and in proper proportions to support their no

Which are the structures that are part of the nervous system, Which are the...

Which are the structures that are part of the nervous system? The structures that form the nervous system can be separated into the central nervous system (CNS) and the periphe

Reagent for separation of amino acid by paper chromatography, Define Reagen...

Define Reagent for Separation of Amino Acid by Paper Chromatography? The following reagents will be required for carrying out the experiment: 1. Amino acid solution- Weig

Name the enzyme present in saliva, Name the enzyme present in saliva and sa...

Name the enzyme present in saliva and say what type of food it acts on.   The enzyme in saliva is salivary amylase and it acts on starch.

What are the segments that form the body of the tapeworm, What are the segm...

What are the segments that form the body of the tapeworm called? What is their function? The body of the tapeworm is made of segments known as proglottids. The proglottids are

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd