Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Emergence of contemporary biology, EMERGENC E OF CONTEMPORARY BIOLOGY - ...

EMERGENC E OF CONTEMPORARY BIOLOGY - 1 .       Aristotle (384-322BC) - Greek Classified animal species and arranged them in hierarchies. Formulated 'Great chain of

Invertebrates, describe the phylums of invertebrates?

describe the phylums of invertebrates?

Symptoms of chronic gastritis, Q. Symptoms of chronic gastritis? These ...

Q. Symptoms of chronic gastritis? These include anorexia, chronic fatigue, and feeling of fullness, belching, vague epigastric pain, nausea and vomiting and passage of black ta

Define about the centrifuge, Define about the Centrifuge? Centrifuge is...

Define about the Centrifuge? Centrifuge is an apparatus consisting essentially of a compartment spun about a central axis to separate contained materials of different specific

Role of exercise in the management of diabetes mellitus, Role of exercise i...

Role of exercise in the management of diabetes mellitus Exercise is another important component of life style modification. Like diet control, regular exercise is important in

Define metabolic aberrations and clinical manifestations, Define Metabolic ...

Define Metabolic Aberrations and Clinical Manifestations? The state of obesity brings about certain alterations in the normal body processes which are enumerated herewith and h

Cultural and religious values, Wildlife has influenced language, art, relig...

Wildlife has influenced language, art, religion and social customs of many societies worldwide, and wild animals figure prominently in many cultures even today. In all cultures of

Explain the function of muscular tissue, How can the presence, localization...

How can the presence, localization and function of muscular tissue in beings of the phylum Annelida be explained? In these beings there are a longitudinal muscular layer under

Prevention of malaria, Prevention of malaria No drug for malaria preven...

Prevention of malaria No drug for malaria prevention is 100% effective. Travelers to countries that have malaria should seek prompt medical attention for febrile illness wherea

What are the types of nutrients, Q. What are the types of nutrients? Explai...

Q. What are the types of nutrients? Explain the functions of nutrients? Types of nutrients  • Carbohydrates • Proteins • Fats • Minerals • Vitamins • Water Fu

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd