Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

What are the catalysts, Q. What are the catalysts? Catalysts are substa...

Q. What are the catalysts? Catalysts are substances that decrease the activation energy of a chemical reaction, facilitating it or making it energetically viable. The catalyst

Name the important inorganic molecular for living being, What are the most ...

What are the most significant inorganic molecular substances for living beings? The most significant inorganic substances for living beings are mineral salts, water, carbon dio

FEEDING MECHANISM., EXPLAIN IN DETAILS FEEDING MECHANISM IN MAN.

EXPLAIN IN DETAILS FEEDING MECHANISM IN MAN.

Which is the vertebrate class, Q. Which is the vertebrate class that is con...

Q. Which is the vertebrate class that is considered the first entirely terrestrial? Totally independent from the aquatic habitat, The first entirely terrrestrial vertebrate cla

Neurons, how does sodium and potassium ions maintain the resting petential ...

how does sodium and potassium ions maintain the resting petential of neurons

Define the term - magnetoencephalography, Define the term - magnetoencephal...

Define the term - magnetoencephalography A variant ERP known as magnetoencephalography (MEG) has been developed. MEG, which is still in its infancy, requires upward of 60 elect

Explain about the electrophoresis, Explain about the Electrophoresis? E...

Explain about the Electrophoresis? Electrophoresis refers to the movement of charged particles because of an external electric field. Because charged molecules can be made to m

State the term - multiple sclerosis, Explain about the Multiple Sclerosis ...

Explain about the Multiple Sclerosis This is a disease characterised by the loss of myelin, largely in motor tracts but also in sensory tracts. The loss of myelin is not unifor

Some precautionary measures to avoid addiction, SOME PRECAUTIONARY MEASURES...

SOME PRECAUTIONARY MEASURES TO AVOID ADDICTION - DEADDICTIO N - First phase of treatment is detoxification. Next phase is of psychotherapy and counselling. Deadi

Describe about pulmonary respiration, Q. Besides vertebrates two invertebra...

Q. Besides vertebrates two invertebrate phyla contain species that make pulmonary respiration. Which are these phyla? Terrestrial molluscs and the arachnid arthropods are the i

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd