Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

What characteristics of fatty acids are false, What characteristics of fatt...

What characteristics of fatty acids are false? (Dissolves in water, used for energy storage, used to build lipids, found in triglycerides, found in steroids)?

Are mollusc metameric beings, Are mollusc metameric beings? Exclusively ana...

Are mollusc metameric beings? Exclusively analyzing this feature could it be said that molluscs are evolutionarily proximal to nematodes or to annelids? In molluscs there is no

Annelids, sanguivarous mode of feeding in annelida

sanguivarous mode of feeding in annelida

Illustrate about the term- hypnagogic hallucinations, Illustrate about the ...

Illustrate about the term- Hypnagogic hallucinations  Hypnagogic hallucinations (Greek, 'hypnos' meaning "sleep," and 'gogic' meaning "enter into") are episodes of auditory, vi

Determine the architecture of cell, Determine the architecture of cell ...

Determine the architecture of cell There are over 200 types of cells in the human body, which are assembled into a variety of tissues, such as, the epithelia, connective tissue

Benzene and ether non-polar or polar substances, Q. Are organic solvents li...

Q. Are organic solvents like benzene and ether non-polar or polar substances? the ethers and Benzene are molecules without electrically charged portions and thus they are non-p

Write an account on coenzymes, Question 1 Describe in detail the immunopro...

Question 1 Describe in detail the immunoprophylaxis Question 2 Give a detailed account on autoimmune diseases Question 3 Describe the classification and properties of an

What is inflammatory bowel disease, Q. What is Inflammatory Bowel Disease? ...

Q. What is Inflammatory Bowel Disease? Inflammatory bowel disease is a general term used to refer to chronic inflammatory condition of the intestine. It is applied to three con

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd