Tuberculosis - patients on haart, Biology

Assignment Help:

Patients on HAART

Rifamycins induce hepatic CYP3A4 enzymes and can accelerate metabolism of protease inhibitors and some non-nucleoside reverse transcriptase inhibitors (NNRTIs), decreasing their serum concentrations, possibly to ineffective levels. The degree to which each drug activates CYP3A4 differs: rifampin is the most potent and rifabutin the least. In addition, rifabutin is a substrate for CYP3A4; protease inhibitors slow its metabolism, increasing serum concentrations and possibly toxicity.

 


Related Discussions:- Tuberculosis - patients on haart

Agro industrial-evaluation of feedstuff, Evaluation of feedstuff In th...

Evaluation of feedstuff In the feed manufacturing process evaluation of the feed ingredients is very important in achieving consistent quality throughout the year. If one is a

Solubility of oxygen, Solubility of Oxygen It is also important to kno...

Solubility of Oxygen It is also important to know that solubility of gases decreases with the presence of solutes or increased salinity. Table shows the solubility of oxygen a

What is enzyme assay, What is Enzyme assay Enzyme assay may also be use...

What is Enzyme assay Enzyme assay may also be used to determine whether stored plant products are suitable for use as food commodities, for e.g.  α-amylase should be present

Golgi complex, GOLGI COMPLEX ( GOLGI APPARATUS = GOLGI BODY) The Nobel ...

GOLGI COMPLEX ( GOLGI APPARATUS = GOLGI BODY) The Nobel laureate, Camilla  Golgi (1898)  discovered  the  presence of a special,  small group  of interconnecting  membranous  s

Explain the oxidative phase of the pentose phosphate pathway, With the help...

With the help of reaction briefly explain the oxidative phase of the pentose phosphate pathway. The oxidative branch of the pathway generates NADPH and pentose-5 phosphate, th

Heat energy is liberated during respiration, Some amount of energy is gener...

Some amount of energy is generatred from the oxidation of food materials is released as heat. This can be proved by germinating seeds. Aim: To show that heat is liberated during re

Why is carbon monoxide toxic for humans, Q. Why is carbon monoxide toxic fo...

Q. Why is carbon monoxide toxic for humans? Hemoglobin "likes" carbon monoxide (CO) much more than it likes oxygen. When there is carbon monoxide in the inhaled air it binds to

Explain exotic species, Explain exotic species? Describe with the help ...

Explain exotic species? Describe with the help of two examples how the exotic species disturb the native species of an ecosystem ?

Describe open circulatory system, Q. What is an open circulatory system? ...

Q. What is an open circulatory system? Open circulatory system is the one in which blood doesn't circulate only inside blood vessels but it also falls in cavities that irrigate

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd