Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Steroid and Thyroid Hormones
Cytoplasmic receptors for steroids are proteins with two subunits that bind to the steroid molecules. When both receptor sites are occupied by the steroid then the receptor-steroid complex migrates to the nucleus where one subunit ensures that the complex binds to the specific site on the chromatin. Then the receptor subunits separate and the other subunit interact directly with the adjacent region of DNA molecule resulting in the transcription of the DNA segment into mRNA.
Thyroid hormone acts in a similar manner except that the receptor is located in the nucleus. The major hormone secreted by thyroid is thyroxine (T4). It travels in blood attached to carrier proteins. Thyroid also secretes a small amount of triiodothyronine (T3). Carrier proteins have higher affinity for T4 and very little T4 is free in the plasma. Only the free T4 and T3 enter the cells. The rest of the bound T4 acts as a reservoir for slow release. The free T4 that enters the cell s also converted to T3 enzymatically. Therefore, T3 is the chemically more potent and active form of thyroid hormone.
Figure:Steroid and Thyroid Hormones
Asymptomatic patient: The current opinion is that in asymptomatic patients with left ventricular dysfunction and severe MR surgery should not be delayed. The echo cardiographic a
Explain Transposition with VSD and Pulmonary Stenosis ? In the early years Rastelli and le Compte operations had 20 to 30 per cent mortality. This has been reduced to 5 per c
Q. What is the difference between temporal summation and spatial summation of muscle fibers? What is tetany? Spatial summation is the recruiting of new muscle fibers to incr
A saline drip is to be prepared for a lab experiment that is looking at hydration in lab rats. Calculate the amount of NaCl need to make 4 liters of a 0.9% solution.
What are the main prophylactic measures against schistosomiasis? The main measures to stop schistosomiasis are: information for infected individuals to look for treatment and t
Stages of Research Process: Planning Stage The planning stage of research process includes a series of interdependent steps consisting of 1) conceptualizatioq of the r
The most recent blood work of a patient with a diagnosis of acute myelogenous leukemia (AML) reveals thrombocytopenia. Where is the patient most likely to experience abnormal bleed
The evolutionary species concept which identifies a species as a "lineage (i.e. ancestor descendant sequence of population) evolving separately from others with its own unitary ro
Neuston - Aquatic Ecosystem These are unattached organisms which live at the air-water interface such as floating plants and several types of animals. Some spend most of their
Explain Class Bivalvia in animal kingdom? This name of this Class reflects the group's most distinguishing feature. Clams, oysters, scallops and mussels all have two shells tha
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd