Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Define about skeletal system, Define about Skeletal system Skeletal sy...

Define about Skeletal system Skeletal system provides framework to the body; supports the soft tissues; protects delicate organs. The skeletal system is made up of bones an

Automated dna sequencing, Automated DNA sequencing is now common place whic...

Automated DNA sequencing is now common place which is based on the chain termination method but using a fluorescent dye attached to an oligonucleotide primer instead of using radio

Determine the term mentalis, Mentalis The mental tubercles on either si...

Mentalis The mental tubercles on either side of mental protruberance(in midline) gives origin to the mentalis muscle. Above the mentalis origin, the incisivus muscle takes orig

Vivipary - development biology, Vivipary - Development Biology In flow...

Vivipary - Development Biology In flowering plants the seed or fruit generally is dispersed and germination occurs when the conditions are congenial for growth. However, in so

Biostatistic.., biostatistical application in biotechnology

biostatistical application in biotechnology

Use values of biodiversity, Despite its importance, determining the value o...

Despite its importance, determining the value or worth of biodiversity is complex and often a cause for debate. This is largely due to the fact that the worth placed on biodiversit

Respiration, difference between the respiration occurs in lower and higher ...

difference between the respiration occurs in lower and higher organisms

Zoonotic diseases-japanese encephalitis, Japanese encephalitis Japanes...

Japanese encephalitis Japanese encephalitis (JE) is a mosquito-borne encephalitis and is caused by  flavivirus belonged to the family Flaviviridae. It is a zoonotic disease, i

Mechanism of gastrulation, MECHANISM OF GASTRULATION - It is most im...

MECHANISM OF GASTRULATION - It is most impotant stage of embryonal development, in which single layered blastula converts into 2 or 3 layered gastrula. During this stage,

Urine sugar testing, Testing for urine sugars is not recommended for either...

Testing for urine sugars is not recommended for either diagnosis or monitoring of patients with diabetes. This is because a urine sugar is not a reliable test. When no facilities a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd