Sickle Cell, Biology

Assignment Help:
Sickling occurs in deoxyhemoglobin S, but not in oxyhemoglobin S. Oxyhemoglobin has a small hydrophobic \"pocket\" in a ß chain region located in the interior of the protein. In deoxyhemoglobin, however, this pocket is located on the surface of the protein. In deoxyhemoglobin S, Val 6 interacts with this surface pocket leading to aggregation of HbS. Choose two amino acids that would be reasonable candidates for the pocket-Val 6 interaction.

Related Discussions:- Sickle Cell

Autotomy and regeneration, Autotomy and Regeneration Shedding of body...

Autotomy and Regeneration Shedding of body parts in self-defense to avert the attention of the predator-enemy or in any other emergency is a type of autotomy (auto: self, tom

Define the drug and drug effect, Define the Drug and Drug Effect? In th...

Define the Drug and Drug Effect? In the discussions above, we reviewed the effect of food on drug metabolism. Interestingly, not only can drugs interact with food and alcohol,

Factors affecting water requirements of microorganisms, Q. Factors Affectin...

Q. Factors Affecting Water requirements of microorganisms? Factors that may affect aw requirements of microorganisms include: 1. Kind of solute employed to reduce the aw: F

Maintain nutrition in diarrhoea, Maintain nutrition Your responsibilit...

Maintain nutrition Your responsibility as a nurse is to take care of nutrition and prevent the child from starvation. Breast feeding'should be continued during the diarrhoea e

Bacteria - type of microorganisms, Q. Bacteria - type of microorganisms? ...

Q. Bacteria - type of microorganisms? Many of us know bacteria only as "germs," invisible to naked eyes that can invade our bodies and make us sick. Few know that many bacteria

Shoot multiplication -clonal propagation, Shoot Multiplication -Clonal Prop...

Shoot Multiplication -Clonal Propagation This is the most important step with respect to the rate of propagation and genetic uniformity of the product. The most reliable and

The reproductive system of house fly, The reproductive system of house fly:...

The reproductive system of house fly: In houseflies seperate male and female organisms are present. Male housefly reproductive system. The male hothe reproductive syste

Define pacinian corpuscules, Q. Define Pacinian corpuscules? Pacinian ...

Q. Define Pacinian corpuscules? Pacinian corpuscules are an example of sensory receptors scattered deep in the subcutaneous tissue underlying skin or in viscera.  These mech

Open pulmonary valvotomy-types of surgery, Open Pulmonary Valvotomy :  ...

Open Pulmonary Valvotomy :  Open pulmonary valvotomy by technique of inflow occlusion is done without cardio pulmonary bypass. Surface hypothermia is used and inflow occlusio

How biocompatibility of materials affect osseointegration, Q. How Biocompat...

Q. How Biocompatibility of materials affect osseointegration? Materials available of present are cpTi (commercially pure Titanium) Ti - 6AI - 4V (Titanium - 6 Aluminum - 4 Vana

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd