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Benzathine penicillin given every three weeks as IM injection (1.2 mega units) has given the best results. Oral agents (penicillin V) are given in patients with lower risk of rheumatic recurrence. In patients with penicillin allergy, sulphadiazine or erythromycin is used. According to ICMR recommendation, secondary prophylaxis should be carried out till 35 years of age. As per American Heart Association (AHA, 1995), the recommendations vary for secondary rheumatic prophylaxis. In general it is recommended that patients with established rheumatic heart disease, should receive prophylaxis till 10 years after the last episode or 40 years of age, which ever is longer. Some patients who develop post streptococcal reactive arthritis without carditis are given Benzathine penicillin 1.2 mega units ever three weeks for 1 year.
Ross Operation : In this technically demanding operation, the aortic valve is replaced by patient's own pulmonary valve (autograft) and a pulmonary or aortic allograft (homo
Define Hydration Properties of Proteins? General conformation of individual proteins in solution is largely dependent on the interaction with water. The progressive hydration o
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What are the functions of the spleen? Why is a total splenectomy (surgical removal of the spleen) compatible with life? The spleen has many functions: it participates in the de
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