Ribonucleases and deoxyribonucleases, Biology

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Ribonucleases  and  deoxyribonucleases

These enzymes  are  responsible  for  the degradation of  dietary  nucleic acids. Ribonucleases  and  deoxyribonucleases secreted by  the pancreatic juice  hydrolyze RNA  and  DNA  to  oligonucleotides.  These  are  further  hydrolyzed  by  pancreatic phosphodiesterases producing a mixture of 3' and 5' mononucleotides. Nucleotidases remove  the phosphate groups hydrolytically releasing nucleosides. 

 


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