Proximal convoluted, Biology

Assignment Help:

Proximal Convoluted

Tubule The glomerular filtrate, which is isosmotic to plasma, enters the proximal convoluted tubule where its volume is reduced by about 80%. This reduction in fluid v6lume is 'accomplished by the active reabsorption of NaCl, glucose, amino acids, etc. from the tubular fluid. As these solutes are removed, the tubular fluid becomes hypoosmotic and the interstitial fluid surrounding the tubular wall becomes hyperosmotic. This causes passive diffusion of water out of the tubule to restore isosmotic condition between the tubular fluid and the surrounding cortical interstitium.

This reabsorption of water is secondary to solute transport and occurs inevitably irrespective of the water requirements of the body. Hence, it is called the obligatory reabsorption of water. Thus, in the proximal convoluted tubule, there is a drastic reduction in fluid volume without any change in its osmolarity. At the normal plasma glucose concentration of 100 mg per 100 ml, glucose is totally reabsorbed from the ultrafiltrate in the proximal convoluted tubule. If the plasma glucose concentration increases above the .normal level, its concentration in the ultrafiltrate also increases correspondingly. If it exceeds, the capacity of the transport mechanism to reabsorb, some glucose appears in the urine as happens in diabetic patients.


Related Discussions:- Proximal convoluted

Vertebrates, characterstics and classification of vertebrates

characterstics and classification of vertebrates

The splinter with a sterile needle, joey has a splinter in his finger. His ...

joey has a splinter in his finger. His mother pulled the skin away from the splinter with a sterile needle and removed the splinter. Joey did not feel pain and did not bleed. Expla

Homomorphic types - intra specific incompatibility, Homomorphic Types - Int...

Homomorphic Types - Intra specific Incompatibility It is characterized by morphologically indistinguishable mating types within a species. A proper breeding is required for th

Evaluate the magnitude of st depression, Q. Evaluate the Magnitude of ST De...

Q. Evaluate the Magnitude of ST Depression? It is intuitive that the magnitude of ST depression should correlate with the degree of the ischaemia. In patients with left main or

Does natural selection produce an effect directly on genes, Does natural se...

Does natural selection produce an effect directly on genes, on genotypes, or on phenotypes? Explain please.

Explain the treatment of susceptible tb, Treatment of susceptible tb Al...

Treatment of susceptible tb All isolates of Mycobacterium tuberculosis should be tested for antimicrobial susceptibility, but results generally do not become available for at l

Phototropism, wich variables are controlled when conducting a phototropism ...

wich variables are controlled when conducting a phototropism experiment

What is the monohybridism, What is the monohybridism? The Monohybridism...

What is the monohybridism? The Monohybridism is the study of only one characteristic in the crossing of two pure individuals (hybridization) for that characteristic.

Explain procedure for analysis of air of processing facility, Explain Proce...

Explain Procedure for Analysis of Air of Processing Facility? Now conduct the experiment following the steps enumerated herewith: 1. Label the Petri plates with nutrient aga

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd