Proximal convoluted, Biology

Assignment Help:

Proximal Convoluted

Tubule The glomerular filtrate, which is isosmotic to plasma, enters the proximal convoluted tubule where its volume is reduced by about 80%. This reduction in fluid v6lume is 'accomplished by the active reabsorption of NaCl, glucose, amino acids, etc. from the tubular fluid. As these solutes are removed, the tubular fluid becomes hypoosmotic and the interstitial fluid surrounding the tubular wall becomes hyperosmotic. This causes passive diffusion of water out of the tubule to restore isosmotic condition between the tubular fluid and the surrounding cortical interstitium.

This reabsorption of water is secondary to solute transport and occurs inevitably irrespective of the water requirements of the body. Hence, it is called the obligatory reabsorption of water. Thus, in the proximal convoluted tubule, there is a drastic reduction in fluid volume without any change in its osmolarity. At the normal plasma glucose concentration of 100 mg per 100 ml, glucose is totally reabsorbed from the ultrafiltrate in the proximal convoluted tubule. If the plasma glucose concentration increases above the .normal level, its concentration in the ultrafiltrate also increases correspondingly. If it exceeds, the capacity of the transport mechanism to reabsorb, some glucose appears in the urine as happens in diabetic patients.


Related Discussions:- Proximal convoluted

Thyroid, A person has swelling on the front of his neck. Name the disease h...

A person has swelling on the front of his neck. Name the disease he is suffering from and the cause of it.

Leptospirosis, Leptospirosis Synonyms: Weil’ disease, canicola fever...

Leptospirosis Synonyms: Weil’ disease, canicola fever, 7-day fever Leptospirosis is an important and widespread zoonosis. It was first described by Adolf Weil in 1886 when h

Puberty, how does the hypothalamus begin puberty

how does the hypothalamus begin puberty

Phylum porifera, harmful and beneficial usesa of phylum porifera

harmful and beneficial usesa of phylum porifera

Which is the brain regions associated with memory, Q. Which is the brain re...

Q. Which is the brain regions associated with memory? According to researchers some of the major regions of the nervous system associated with the memory phenomenon are the hip

What is end-to-end anastomosis subclavian flap aortoplasty, What is End-to-...

What is End-to-End Anastomosis with Subclavian Flap Aortoplasty ? The two operations can be combined as a single procedure. Medially end-to-end anastomosis is done between the

Side effects of sedatives and hypnotics, Side Effects of Sedatives and Hypn...

Side Effects of Sedatives and Hypnotics: Side effects are same  like anti anxiety drugs such as hypotension, palpitation, syncope (fainting), change in libido, physical or psy

Atrial arrhythmias-peri operative problems, Atrial Arrhythmias :  Atl...

Atrial Arrhythmias :  Atlial fibrillation is the most common rhythm abnormality after CABG. Paroxysmal atrial tachycardia and atrial flutter are less common. Increased sympat

What is standard operating procedure manual (sop), Question 1 What is s...

Question 1 What is standard operating procedure manual (SOP)? Do you think it is important to maintain SOPs in all the laboratories? List the advantages of maintaining SOPs in

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd