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The RER have various proteins which have the role of assisting nascent proteins to fold rightly into their native conformation. Some of these are called as chaperones. RER-resident proteins are made on the RER and either pass into the lumen (as do secretory proteins) or are anchored in the membrane as for Type I integral membrane proteins. Furthermore, these proteins have a retention signal at the C terminus which is recognized by specific receptor proteins which retain these proteins in the RER, avoiding them from moving between the secretory pathway to the Golgi. In case of the soluble proteins in the lumen of the RER the retention signal is Lys-Asp-Glu-Leu or KDEL using the one-letter amino acid code at the C terminus. In case of the Type I integral membrane proteins in the RER membrane the retention signal is KKXX (Lys-Lys-Xaa-Xaa) in the cytosolic C terminus.
Why are the recombinant DNA technology and the nucleus transplantation technology still dangerous? The recombinant DNA technology and the nucleus transplantation technology (cl
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In a properly functioning negative feedback system, the A. value of the controlled variable will always be very close to the threshold value when the system is in steady state.
Q. What are the Keys for Identifying plants and animals? Keys are determined as devices to help in identifying plants and animals. These are merely an aid to identification bas
Is there a respiratory pigment in the annelid blood? The blood in beings of the phylum Annelida have the respiratory pigment hemoglobin (the similar found in chordates) and oth
Take the prepared slide of Euglena and focus it first under low power and next under the high power of tlie microscope. Observe tlie following characteristics: i) Euglena is an
Q. What are the cells responsible for the production of antibodies? The cells that produce antibodies that is the cells of the humoral immune system are the B lymphocytes (B ce
Bone Surfaces: There are four major bone surfaces: 1) Periosteal (outer surface of all bones) 2) Endosteal (inner surface of cortical bone) 3) Haversian (inner surface o
Q. Nutrition Support for myocardial infarction patient? The nutrient requirements of a MI patient vary from time of getting hospitalized in an emergency to the time of getting
How did Darwin reach the principle of natural selection from the observation of differences among individuals of the same species? The Darwin recognized that in a same species
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