Pathophysiology of constrictive pericarditis, Biology

Assignment Help:

Q. Pathophysiology of constrictive pericarditis?

Ans.

The thickened and rigid pericardium causes constriction of the heart and restricts ventricular dialatation and diastolic filling of the ventricles. The thickened rigid pericardium can cause dissociation of intracardiac and intrathoracic pressures and elevation of diastolic intracardiac pressures. This results in systemic and pulmonary venous congestion. Since the early phase of ventricular relaxation is normal, the early filling of the ventricles take place normally. Further relaxation of ventricles are restricted by the thickened pericardium resulting in acute elevation of diastolic ventricular pressure which gives a square root (") appearance to the diastolic ventricular pressure tracing. Uniform constriction of all the four cardiac chambers results in equalization of diastolic pressures in all the four chambers. This is different from restrictive cardiomyopathy where the difference in diastolic pressure between ventricles will be more than 5 mm. of Hg. The myocardium is usually normal in structure and function. This results in good systolic function.

The ventricular filling takes place during early filling phase only as further filling is prevented by the thickened and rigid pericardium.


Related Discussions:- Pathophysiology of constrictive pericarditis

Do enzymes act better under acid or basic ph, Do enzymes act better under a...

Do enzymes act better under acid or basic pH? Most enzymes act in pH among 6 and 8, a range that corresponds to the general acidic level of cells and blood. There are enzymes,

Mucopolysaccharides, MUCOPO L YSACCHARIDES They are heteropolysacc...

MUCOPO L YSACCHARIDES They are heteropolysaccharides of high molecular weight that are gelatinous is consistency, functioning in lubrication and as sticky substances in or

What are the pupillary defects, What are the Pupillary defects There ar...

What are the Pupillary defects There are certain deviations  from normal pupillary reflexes which point towards certain specific pathology.

Ability of mammalian kidney, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Slight or no metamorphosis, Slight or no Metamorphosis In primitive w...

Slight or no Metamorphosis In primitive wingless insects (Apterygota) such as spring tails, silver fish etc. and in secondarily apterous insects the young ones which hatch fr

Metabolic significance of hmp pathway, Metabolic Significance of HMP Pathwa...

Metabolic Significance of HMP Pathway Having gone  through  the HMP pathway, you would have got  some idea about the significance  of this alternative oxidative  pathway for  t

Addition of glycine to the physiological saline, Addition of glycine to the...

Addition of glycine to the physiological saline A complete motor neuron is removed from a frog and placed in a large volume of normal physiological saline.  The neuron is heal

Sunlight used for sterilization, Q. Sunlight used for sterilization? It...

Q. Sunlight used for sterilization? It possesses appreciable bactericidal activity under natural condition. The action is primarily due to content of the ultraviolet rays; howe

Can you explain hormones, Q. What are hormones? Hormones are substances...

Q. What are hormones? Hormones are substances collected by the circulation and secreted by the endocrine glands that act to produce effects upon specific tissues and organs and

How is the cerebrum anatomically divided, How is the cerebrum anatomically ...

How is the cerebrum anatomically divided? The cerebrum is divided into two cerebral hemispheres, the right and the left. Each hemisphere is made of four cerebral lobes: frontal

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd