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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
What is the Importance of vitamin B 12 Vitamin B 12 deficiency is manifest by the symptoms of pernicious anaemia (Addison-Biermer's disease). An irreversible atrophy of the
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Define Iron Status of the Individual Lastly, iron status of the individual is a floury determinant of how much iron is absorbed. On a mixed diet with some haem iron, the overal
Autoradiography is the process to detect radioactively labeled molecules (which commonly have been separated in an SDS-PAGE or agarose gel) based on their ability to develop an im
The vast amount of genomic DNA in a eukaryotic cell is strongly packaged in chromosomes having within a specialized organelle and the nucleus. This very vast amount of e
Q. Are there any bacteria made of more than one cell? There are no pluricellular bacteria. All bacteria are unicellular prokaryotic.
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What is Posterior Aneurysm? The technique of Posterior Aneurysm operation is the same. Care must be taken to avoid injury to the posterior papillary muscle and poster
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