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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
Why is the cytoplasm of sperm cells very reduced? Why do mitochondria of sperm cells concentrate in the base of the flagellum ? The decreased cytoplasm of sperm cells reduces th
Now try to pull the strands apart at the "origin of replication." What happens to the DNA molecule when the ends are restricted
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