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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
Q. Long-term treatment of maple syrup urine disease? Special feeds containing energy and proteins without the branched chain amino acids can be given to the infants. In some in
HUMA N CHROMOSOMES The normal diploid (2N) chromosome number in human being is 46. It was given by T.H. Tjio and A. Levan in 1956. The chromosome complement of a cel
Determine the Clinical use of brain imaging in disease management Clinical use of brain imaging in disease management has also grown, driven by broader availability of scannin
Define the Dietary Management for Underweight? We just read about the etiological factors that may lead to undernutritioin and weight loss. Whatever may be the cause, all under
What is meant by the law of use and disuse and by the law of the transmission of acquired characteristics? As per to the law of use and disuse the characteristics of a body var
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Risk Factor Modification : Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of
Pattern of Limb Development The first visible sign of limb development is the appearance of ridge or thickening on each lateral side of the embryo of amniotes. The ridge call
classification of protozoa
There are three levels of diversity viz. genetic, species and ecosystem diversity. In effect, these levels cannot be separated. Each is important, interacting with a nd influencin
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