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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
Cancer ; Cell division , like all other biological processes, is under genetic control. Certain genes must regulate the processes of cell growth and division in respons
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Risk Factor Modification : Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of
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