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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
Epidemiological studies The use of available data from the positive epidemiological studies in the risk assessment is encouraged. Data derived fiom human clinical studies, s
Assume that you have a stock solution of epinephrine at a concentration of 1mg/ml. Further assume that there are 20 drops/ml. a. Calculate the number of drops of the stock solution
What are ganglia? Ganglia (singular ganglion), or neural ganglia, are structures located outside the central nervous system (for instance, beside the spinal column or near visc
Determine the Strengths of Full Battery Measures 1) Wide range of scores allow differential diagnosis in various cognitive disorders 2) More reliable, and sensitive 3) Br
Kidney Disease The target BP in chronic kidney disease is set at 130/80. This will retard the progression of renal function. The drugs recommended are the ACEI/ARBs. These c
Spring overturn - Overturn In spring and early summer season the increased solar radiation melts the ice cover, which, as it attains a temperature of 4° Celsius, becomes dense
Explain Dental Care Delivery System In the dental care delivery system: there are: patients, insurance payers and dentists For patients: Success = function + esthetics
Zinc (Zn) - Micronutrients In its function in some enzyme systems, zn 2+ resembles Mn 2+ in that it brings about substrate binding and conformational changes in enzymes. A n
With the exception of those soft drinks that contain phosphoric acid, in most other acidic foods acidity is due to the presence of weak organic acids. These do not dissociate comp
Colibacillosis Colibacillosis is caused by different strains of Escherichia coli. The disease mainly affects children and travelers. Organisms grow in gut and produce toxin. It ma
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