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Q. Mismatch and Recombinational repair?
Mismatch repair:
1. Mismatches can take place when DNA polymerase inserts wrong nucleotide during replication 2. Mismatch repair is"coupled" to replication
Recombinational repair:
1. Takes place during DNA replication 2. Major steps: (a) DNA polymerase skips over damaged DNA leaving a gap opposite the lesion (b) Undamaged parental strand recombines into the gap (this is facilitated by recA protein in E. coli) (c) the new gap in parental strand is filled by DNA polymerase and ligase.
Adverse Effects of Ribavirin Systemic ribavirin has been associated with hemolytic anemia. Oral ribavirin plus interferon appears to cause a higher incidence of cough, pruritu
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what is the function of the bladder in the bladder worm
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Uncompetitive inhibition In this type of inhibition, the inhibitor only binds with the enzyme-substrate complex making it inactive. As a result, the product formation
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