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This is extension of the EM algorithm which typically converges more slowly than EM in terms of the iterations but can be much faster in the whole computer time. The general idea o
Quincunx is the device used by Galton to illustrate his lectures, which is shown in the Figure. It had a glass face and a funnel at its top. The shot was passed through funnel an
Case-control study : The traditional case-control study is the common research design in the epidemiology where the exposures to risk factors for cases (individuals getting the dis
Regression through the origin : In some of the situations a relationship between the two variables estimated by the regression analysis is expected to pass by the origin because th
Reciprocal transformation is a transformation of the form y =1/x, which is specifically useful for certain types of variables. Resistances, for instance, become conductances, and
Chernoff's faces : A method or technique for representing the multivariate data graphically. Each observation is represented by the computer-created face, the features of which are
Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might
A family of the probability distributions of the form given as here θ is the parameter and a, b, c, d are the known functions. It includes the gamma distribution, normal dis
Hazard regression is the procedure for modeling the hazard function which does not depend on the suppositions made in Cox's proportional hazards model, namely that the log-hazard
Protocol is the formal document outlining the proposed process for carrying out the clinical trial. The basic features of the document are to study the objectives, patient selecti
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