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Infectious bovine rhinotracheitis (IBR)
The disease is caused by a Bovine Herpesvirus -I belonging to the family Herpesviridae and subfamily Alphaherpesvirinae. It is a DNA virus spherical in shape, enveloped and cubical in symmetry, with linear double stranded DNA of 125-235 kbp in size. The virus replicates in the nucleus and hence intra-nuclear inclusion bodies are formed. BHV-1 (infectious bovine rhinotracheitis-IBR; infectious pustular vulvovaginitis-IPVV) causes a variety of diseases in cattle, including rhinotracheitis, vulvovaginitis, abortion or balanoposthitis and conjunctivitis in cattle and buffaloes. Serology and virus isolation showed presence of this disease in India.
Empiric Initial Therapy Until susceptibility results are available, empiric initial treatment consists of a 4-drug regimen of isoniazid, rifampin, pyrazinamide and ethambutol.
Intravenous Route This route of administering drugs is becoming more popular in the paediatric practice. Purpose of this Route When rapid action is required.
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