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Infectious bovine rhinotracheitis (IBR)
The disease is caused by a Bovine Herpesvirus -I belonging to the family Herpesviridae and subfamily Alphaherpesvirinae. It is a DNA virus spherical in shape, enveloped and cubical in symmetry, with linear double stranded DNA of 125-235 kbp in size. The virus replicates in the nucleus and hence intra-nuclear inclusion bodies are formed. BHV-1 (infectious bovine rhinotracheitis-IBR; infectious pustular vulvovaginitis-IPVV) causes a variety of diseases in cattle, including rhinotracheitis, vulvovaginitis, abortion or balanoposthitis and conjunctivitis in cattle and buffaloes. Serology and virus isolation showed presence of this disease in India.
what year did virchow state where a cell exists there must have been a pre-existing cell
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