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Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting joint null hypothesis.
The fraction of the observed significances at the given α-level is compared to the expected fraction under the joint null and the difference between the two quantities is standardized and this standardized value then maximized over the range of significance levels to provide the higher criticism statistic. This statistic is efficient in assessing whether n normal means are all zero against the alternative that the small fraction is nonzero.
Markers of disease progression : Quantities which form a general monotonic series throughout the course of the disease and assist with its modelling. In uasual such quantities are
Initial data analysis (IDA): The first phase in the examination of the data set which comprises number of informal steps including the following steps * checking the quality o
Length-biased data is a data which arise when the probability that an item is sampled is proportional to its own length. A main example of this situation occurs in the renewal the
This is the branch of mathematics which deals with the theory of contests between two or more players under the specified sets of rules. The subject supposes a statistical aspect w
Cochrane collaboration : An international network of the individuals committed to preparing , maintaining and disseminating the systematic reviews of the effects of the health care
Input to the compress is a text le with arbitrary size, but for this assignment we will assume that the data structure of the file fits in the main memory of a computer. Output of
O'Brien's two-sample tests are the extensions of the conventional tests for assessing the differences between treatment groups which take account of the possible heterogeneous nat
Data which occur when failure period is recorded which are dependent. Such type of data can arise in number contexts, for instance, in epidemiological cohort studies in which th
Inliers is the term used for the observations most likely to be subject to error in situations where the dichotomy is developed by making a ‘cut’ on an ordered scale, and where th
Minimization is the method or technique for allocating patients to the treatments in clinical trials which is usually the acceptable alternative to random allocation. The procedur
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