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To synthesize glycogen two enzymes are needed:
1. UDP-glucose pyrophosphorylase catalyzes the synthesis of UDP-glucose from UTP and glucose 1-phosphate:
The pyrophosphate (PPi) is right away hydrolyzed by inorganic pyrophosphatase, releasing energy. Thus the whole reaction is very exergonic and essentially irreversible.
2. Glycogen synthase now transfers the glucosyl residue from UDP-glucose to the C4 OH group at the nonreducing end of a glycogen molecule, forming a α1-4 glycosidic bond. Amusingly, glycogen synthase can only extend an existing chain. Thus it needs a primer; this is a protein called as glycogenin. Glycogenin holds eight glucosyl units linked via α1-4 link- ages, which are added to the protein by itself for instance Autocatalysis. It is this molecule which glycogen synthase then extends. Each glycogen granule have only a single glycogenin molecule at its core. The reality that glycogen synthase is fully active only when in contact with glycogenin limits the size of the glycogen granule.
Explain about the Incidence of defects in color vision Defects in colour vision can either be congenital or acquired. Males are more affected than females. Out of the populatio
Nuclear endosperm in angiosperm.
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There are different types of insulin available and prescribed by the doctor according to the need of the patient. Insulin is grouped according to the speed of action in the body i.
EMERGENC E OF CONTEMPORARY BIOLOGY - 1 . Aristotle (384-322BC) - Greek Classified animal species and arranged them in hierarchies. Formulated 'Great chain of
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Q. Infants with maple syrup urine disease? Infants with MSUD appear normal at birth. Once they are fed on protein containing feed, they start showing the classic symptoms. Neur
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In chemistry and particularly in biochemistry the fatty acid is a carboxylic acid with a long aliphatic tail (chain) that is either saturated / unsaturated. Many obviously occurrin
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