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Functions of Plasma Proteins
The proteins of the plasma serve several important functions.
Most of the organic constituents of the plasma other than protein represent waste products of metabolism (e.g. urea, uric acid etc.) together with nutritive materials (e.g. amino acids, glucose and fats) absorbed from the intestinal tract. Of the inorganic constituents of plasma, sodium chloride is in highest concentration. Plasma also contains potassium, calcium, magnesium, sodium bicarbonate and minute amounts of iodine and iron. Phosphorus is present in both inorganic and organic forms. The concentration of inorganic phosphorus is about 3 mg and that of the organic form about 40 mg per 100 ml of blood. Potassium is in relatively high concentration in the cells of the blood and in the cells of the solid tissues but is in low concentration in the plasma and the body fluids generally.
Genetic Defect in Pyruvate Dehydrogenase A defed in any of the protein subunits of PDH can result in decrease or complete loss of activity. Severe cases are usually fatal. Sy
Change in nucleus during cleavage
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