Explain the role of lipoprotein, Biology

Assignment Help:

Explain the Role of Lipoprotein ?

As discussed in the previous section, serum concentrations of Lp(a) are elevated in South Asians irrespective of their migrant status. Several studies have documented this elevation in Lp(a) levels in people of Indian origin when compared to other ethnic groups. Higher levels of Lp(a) have been associated with CAD especially if the is concoinitant elevations of LDL levels.

Levels of Lp(a) are largely genetically determined and genetic factors account for over 70 per cent of the variations in the Lp(a) levels in the population. This suggests the basis for a genetic predisposition to CAD among populations with elevated Lp(a) levels and concomitantly raised LDL levels. Proposed mechanisms of atherogenesis by Lp(a) include preferential uptake of Lp(a) into macrophages in atherosclerotic plaaues via binding to fibrin and plasminogen receptors. Because of the structural similarity between Lp(a) and plasminogen, it has also been suggested that the former interferes with plasminogen activation and creates a thrombogenic milieu.


Related Discussions:- Explain the role of lipoprotein

Difference between adrenergic and cholinergic fibre, Difference between Adr...

Difference between Adrenergic and Cholinergic Fibre- S.NO .   1. ADRENERGI C FIBRE   Release nor adrenaline at their CHOLINE

What is trna structure , Transfer  RNA  (tRNA)  molecules  play  an  very s...

Transfer  RNA  (tRNA)  molecules  play  an  very significant  role  in  protein  synthesis. Each tRNA becomes covalently bonded to a particular amino acid  to  create  aminoacyl- t

Nutrition information for two products, In this session's discussion board ...

In this session's discussion board provide links to the nutrition information for 2 products. The nutrition information should be the type you find on the side of a food product th

Explain limited mucosal contact diarrhoea, Q. Explain Limited mucosal conta...

Q. Explain Limited mucosal contact diarrhoea? Limited mucosal contact diarrhoea: It results from situations of inadequate mixing of chyme (semi-liquid mass of food passing thro

What is placebo and nocebo, Problem 1: What is Placebo and Nocebo? Desc...

Problem 1: What is Placebo and Nocebo? Describe the significance of Placebo in clinical trials. Definition of placebo and Nocebo Significance of Placebo in clinical t

Microfilaments - cytoskeletal structures, MICROFILAMENTS Discovered ...

MICROFILAMENTS Discovered by Pelvitz. These are smallest cell structure. These are non-living structures. These are solid structures, consists of actin protein (c

Describe the formation of egg cells from germ cells, Q. Indicating the name...

Q. Indicating the name and respective ploidy of each involved cell how can the formation of egg cells from germ cells be described? The formation of egg cells begins with a ger

Explain about the physiology of eyelid movements, Explain about the physiol...

Explain about the physiology of eyelid movements. Physiology of Eyelid Movements: It is quoted that the eyelids move more than any other part of the body. The major movem

Explain the procedures involved in blood doping, Describe the procedures in...

Describe the procedures involved in blood doping. What are the physiological mechanisms behind blood doping that attempt to achieve the desired outcome(s).

Prosthetic valve endocarditis, The risk of PVE is greatest during the initi...

The risk of PVE is greatest during the initial 6 months after valve surgery (particularly during the initial 5 to 6 weeks) and thereafter declines to a lower but persistent risk (0

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd