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Explain the Role in Insulin Formation?
You are aware that insulin receptors are present in many cells with their concentration being highest in adipocytes (cells present in adipose tissue) and hepatocytes (liver cells). You also know that insulin receptor has two extracellular alpha-subunits and two extracellular beta-subunits. It is the alpha-subunit to which insulin binds. Once insulin binds to the alpha-subunit of the receptor, a specific phosphorylation of the beta-subunit occurs through a cascade of phosphorylation reactions. This leads to increased insulin sensitivity. The enzyme partly responsible for this phosphorylation is the 'insulin receptor tyrosine kinase'. This enzyme is activated by chromium. In rats, removal of chromium has been shown to result in the loss of kinase-potentiating activity. Besides activating the kinase, chromium also inhibits phosphotyrosine phosphatase-an enzyme responsible for inactivation of insulin receptor. The activation of 'insulin receptor tyrosine kinase and inhibition of 'insulin receptor tyrosine phosphatise by chromium would lead to an increased phosphorylation of the insulin receptor, which is associated with increased insulin sensitivity.
Why doesn't a long lasting vaccine against common cold exist yet? Viruses that show a high mutation rate like the virus that causes the common cold escape simply from the actio
Explain in brief about the Cell Membrane All cells, whether prokaryotic or eukaryotic, are bound by a limiting membrane called the cell membrane or the plasma membrane. The ce
translation in eukaryotes..
Q. Photosynthesis rate varies as per to the photic energy intensity. Does the same take place in aerobic respiration? What do happen to the glucose balance as a result of these var
MID BRAIN - Optics lobes 4 in number ( Corpora Quadrizemmini ) in frog corpora bizemmini . Solid, optocoel is absent. 2 superior coculi and 2 inferior coculi are present.
Lipolysis What do we mean by lipolysis? Hydrolysis of ester bonds in lipids is called lipolysis. This may occur by enzyme action or by heat and moisture, resulting in the liber
Write two cytological approaches in taxonomy.
what are disadvantages that protozoan causes
What is gene? Gene is a sequence of DNA nucleotides that codifies the production of a protein.
Anthropometric measurements Anthropometry is the study of the measurement of the human body in terms of the dimensions of bone, muscle, and adipose (fat) tissue. Anthropometric
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