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Explain the Role in Insulin Formation?
You are aware that insulin receptors are present in many cells with their concentration being highest in adipocytes (cells present in adipose tissue) and hepatocytes (liver cells). You also know that insulin receptor has two extracellular alpha-subunits and two extracellular beta-subunits. It is the alpha-subunit to which insulin binds. Once insulin binds to the alpha-subunit of the receptor, a specific phosphorylation of the beta-subunit occurs through a cascade of phosphorylation reactions. This leads to increased insulin sensitivity. The enzyme partly responsible for this phosphorylation is the 'insulin receptor tyrosine kinase'. This enzyme is activated by chromium. In rats, removal of chromium has been shown to result in the loss of kinase-potentiating activity. Besides activating the kinase, chromium also inhibits phosphotyrosine phosphatase-an enzyme responsible for inactivation of insulin receptor. The activation of 'insulin receptor tyrosine kinase and inhibition of 'insulin receptor tyrosine phosphatise by chromium would lead to an increased phosphorylation of the insulin receptor, which is associated with increased insulin sensitivity.
Describe the main cycle in metabolism of cornea. Main Cycle: Glycolysis is represented by the central chain and involves the anaerobic conversion of glucose into pyruvic
Alterations occurring in fruits and vegetables You may already be aware that fruits and vegetables vary greatly in their chemical composition. Though, some generalizations are
Why do leaves change color? Leave is the food factories of plants. During the spring and summer, leaves are actively making food and they are filled with chlorophyll, which giv
What is Intercellular Communication explain briefly? Both plant and animal cells have developed means of communication between cells. In animals, specialized areas of the cell
Describe the term - Intellectual Processes scales The 269 items are divided into 11 content scales, each of which may be administered individually. Since these scales contain v
ARTERIAL SYSTEM OF MAMMAL Basic plan from origin to distribution is similar in all vertebrates as per the mode of respiration. Main anterior aorta in terrestrial forms ar
Explain Pancreatitis Pancreatitis :- Inflammation of the pancreas.
SOM E COMMON REFLEXES RELATED TO RESPIRATION - 1. Cough Reflex: Due to stimulation in Trachea before it 2.5 lit. air is inhaled. 2. Sneezing Reflex: Stimulati
State the series of stimuli ERPs a series of stimuli such as tones or light flashes are presented to the participant, and the raw EEG for a precise one or two second period fol
Q. What is wall resistance of plant cells? Does this resistance make difficult the entrance of water into the cell or facilitate? Turgor Pressure TP, or Wall resistance, is the
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