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Explain the Role in Insulin Formation?
You are aware that insulin receptors are present in many cells with their concentration being highest in adipocytes (cells present in adipose tissue) and hepatocytes (liver cells). You also know that insulin receptor has two extracellular alpha-subunits and two extracellular beta-subunits. It is the alpha-subunit to which insulin binds. Once insulin binds to the alpha-subunit of the receptor, a specific phosphorylation of the beta-subunit occurs through a cascade of phosphorylation reactions. This leads to increased insulin sensitivity. The enzyme partly responsible for this phosphorylation is the 'insulin receptor tyrosine kinase'. This enzyme is activated by chromium. In rats, removal of chromium has been shown to result in the loss of kinase-potentiating activity. Besides activating the kinase, chromium also inhibits phosphotyrosine phosphatase-an enzyme responsible for inactivation of insulin receptor. The activation of 'insulin receptor tyrosine kinase and inhibition of 'insulin receptor tyrosine phosphatise by chromium would lead to an increased phosphorylation of the insulin receptor, which is associated with increased insulin sensitivity.
Q. Why are euglenas involved in polemics related to their taxonomic classification? Euglenas are involved in taxonomic polemics because they tend to be classified sometimes as
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Q. Fluoxetine is an antidepressant drug that presents an action mechanism related to the synaptic transmission. What is that mechanism? Fluoxetine is a substance that inhibits
What are niches and competitive exclusion?
Telophase This is the final stage of mitosis in which the mitotic spindle disappears and each polar chromosomal group is reconstituted into a daughter nucleus, A nuc
Q. Explain the Causes of steatorrhoea? The list of possible underlying causes of steatorrhoea includes: • Malabsorption • Malabiorptian of fats in small intestine •
Floating Stage - Hydrarch The pond is now colonised by plant species which are rooted in mud but their leaves reach water surface and float. These are species of Nelumbo, Nymp
3 main stages of bone formation, and explain the process of these 3 stages.
Explain the Basic Concept of Adulteration? Food adulteration is the change in original composition and quality of food by adding, removing or substituting some ingredients of f
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