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Explain the Role in Insulin Formation?
You are aware that insulin receptors are present in many cells with their concentration being highest in adipocytes (cells present in adipose tissue) and hepatocytes (liver cells). You also know that insulin receptor has two extracellular alpha-subunits and two extracellular beta-subunits. It is the alpha-subunit to which insulin binds. Once insulin binds to the alpha-subunit of the receptor, a specific phosphorylation of the beta-subunit occurs through a cascade of phosphorylation reactions. This leads to increased insulin sensitivity. The enzyme partly responsible for this phosphorylation is the 'insulin receptor tyrosine kinase'. This enzyme is activated by chromium. In rats, removal of chromium has been shown to result in the loss of kinase-potentiating activity. Besides activating the kinase, chromium also inhibits phosphotyrosine phosphatase-an enzyme responsible for inactivation of insulin receptor. The activation of 'insulin receptor tyrosine kinase and inhibition of 'insulin receptor tyrosine phosphatise by chromium would lead to an increased phosphorylation of the insulin receptor, which is associated with increased insulin sensitivity.
Deinococcus radiodurans is a bacterium that was isolated from cooling ponds in and around nuclear power plants. It is highly resistant to ionizing radiation. Propose an hypothesis
CHEMICAL PROPERTIES OF SOIL Soil is a highly dynamic system which supports complex chemical reactions. In this heterogeneous systems, the soil solution acts as the medium for c
Explain the Process of IgE-Mediated Allergic Response? Basically, there are three steps involved with the IgE-mediated allergic response These include: Step 1: Sensitizat
Do beings of the class Reptilia perform gas exchange in the same way amphibians do? These beings do not have permeable skin so they do not make cutaneous respiration such as a
Define the Obesity in Children? It is difficult to measure overweight or obesity in children and adolescents because they grow and mature at different rates. Weight status in c
What is Slime Molds in diversity of life? Acrasiomycota and Myxomycota are appropriately named slime molds. They are slimy! The other part of their name comes from the time whe
Food Applications of hemicelluloses The hemicelluloses find their application in food systems as emulsifer, stabilizer and binder in flavor bases, dressings and pudding mixes.
Name few polymers in the eukoratic cell? Name the mummers that make up the DNA? Compare and contrast between mummers of DNA VS monomers of RNA?
Why is the uricotelic excretion essential for avian and reptile embryos? In reptiles and birds the excretory system is uricotelic as uric acid is insoluble, less toxic and sui
evolution of metazoa
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