Explain the future challenges for neuroscience, Biology

Assignment Help:

 

Explain the Future challenges for Neuroscience?

When the analysis of single cells and even networks has progressed very nicely, there still remain many significant questions. At least two of these challenges are related to the transient nature of the dynamics in neurons and brains. Most of the mathematical analysis that has been done to date assumes stationarity both in the inputs to the neurons as in their intrinsic properties. There will be a need to develop few mathematical techniques for dealing with the transient nature of inputs to the nervous system that goes further than simple periodic forcing. More essentially, most modelers assume that the parameters such as the intrinsic membrane conductances and the synaptic conductance are fixed. Though, it has now been established that there is plasticity at many time scales both in the intrinsic dynamics (Turrigiano and Nelson) and in the connections (Bi and Poo, 1998).

So a major challenge in modelling is how this plasticity influences the behaviour of single neurons and networks of neurons in the existence of stimuli. At some level, it is possible to take benefit of the multiple time scales and generate a hierarchy of models in which the averaged results of one step are used in the next. Another significant challenge is in the feedback between perception and action. That is, most theories and modelers treat the sensory system and the motor systems as separate. Though, it is now clear (see for example, Kleinfeld et al, 2002) that the motor output affects the sensory input forming a massive sensorimotor loop. The computational benefits and consequences of these loops stay to be explored.


Related Discussions:- Explain the future challenges for neuroscience

Define precaution-estimation of nitrogen and protein content, Define Precau...

Define Precautions - Estimation of Nitrogen and Protein Content? 1. The apparatus should be airtight to prevent leakage of NH 3 . 2. The tip of the delivery tube should be i

Procedures for diagnosis - nucleic acid hybridization, Nucleic acid hybridi...

Nucleic acid hybridization: This is a process by which a suitably labeled DNA or RNA from a known infectious agent is used to probe its complementary sequence unique to t

Explain energy requirement in postoperative nutritional care, Explain the E...

Explain the Energy requirement in Postoperative Nutritional Care? Adequate calorie intake is critical for successful outcome of surgery and should be provided in the form of ca

What is the function of the iris and of the pupil, What is the function of ...

What is the function of the iris and of the pupil? The iris works like the diaphragm of a photographic camera as it has muscles that contract or relax varying the pupil diamete

What is gel, What is Gels Sol is free flowing liquid at room temperatur...

What is Gels Sol is free flowing liquid at room temperature, when it becomes relatively firm, it is called a gel. There are a number of factors that affect the strengths, elast

What is mass transportation across the cell membrane, Mass transportation i...

Mass transportation is the access or the exiting of substances in or from the cell engulfed by portions of membrane. The fusion of internal substance-having membranous vesicles wit

What is streatorrhoea, Q. What is Streatorrhoea? Streatorrhoea is more ...

Q. What is Streatorrhoea? Streatorrhoea is more common in Crohn's disease due to heal resection. This may favour calcium-fatty acid complex formation and increased excretion. I

Calculate frequencies of heterozygotes, If dimples may be considered a sing...

If dimples may be considered a single-gene dominant trait, and 64% of the population features dimples, calculate the frequencies of heterozygotes and both types of homozygotes, ass

Can you explain the mycorrhizas, Q. What are the mycorrhizas? How does each...

Q. What are the mycorrhizas? How does each participant benefit in this ecological interaction? Mycorrhizas are mutualist ecological interactions between some plants roots and f

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd