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Explain Saquinavir
Saquinavir (SQV, Fortovase, Invirase) - When administered as a single protease inhibitor, a soft-gel preparation (Fortovase) with improved bioavailability and potency has largely replaced the older hard-gelatin capsule formulation (Invirase), which is poorly absorbed. In healthy volunteers, plasma levels of Invirase and Fortovase were comparable when combined with ritonavir, and Invirase was better tolerated (M Kurowski et al, HIV Med 2003; 4:94). In one study, saquinavir 1000 mg b.i.d. combined with ritonavir 100 mg b.i.d. had similar virologic efficacy and superior tolerability compared to indinavir 800 mg b.i.d.
Retained foetal membranes The foetal membranes are normally expelled within 6to 12 hr after parturition in cows and buffaloes. If the foetal membranes are not voided even upto
Name the two hormones produced by the pancreas and say (a) in what circumstances, (b) in what way, they adjust the glucose concentration in the blood.
What are the three main limiting factors of photosynthesis? The three major limiting factors of photosynthesis process are light intensity, carbon dioxide concentration and tem
gaseous exchange in man
Currents in Estuaries Currents in estuaries are caused primarily by tidal action and river flow. Currents are generally confined to channels but velocities up to several knots
What is absorption? Absorption involves the transfer of materials through the mucosa of the alimentary tract into blood and lymph vessels.
State about the blood ocular barriers of the eye? Blood Ocular Barrier: All vascular beds of the eye are highly permeable to lipoid soluble substances (oxygen, carbon dio
Explain Functional property of WaterBinding/ Hydration Mode of action Proteins can help reduce formula costs as the proteins hold additional water. Food system
Define Disadvantages of using yeast as a source of protein? 1. Less protein yield (45-60%) 2. Growth rate is low (1-3 h) 3. High nucleic acid content leading to the forma
The following progeny genotypes were observed: 73 AaBb, 64 aabb, 279 Aabb, 303 aaBb. Using a chi-square test, test whether these two loci show independent assortment? How would
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