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Protease inhibitors (PIs)
Protease inhibitors prevent cleavage of protein precursors essential for HIV maturation, infection of new cells and viral replication. Use of a protease inhibitor in combination with other drugs has led to marked clinical improvement and prolonged survival even in patients with advanced HIV infection. Most protease inhibitors potently suppress HIV in vivo. Combinations of two protease inhibitors are increasingly being used; one is usually ritonavir, which inhibits the metabolism and increases serum concentrations of other PIs.
Determine sequence weights for the sequences ACTA, ACTT, CGTT, and AGAT in problem 1 by using Thompson, Higgins, and Gibson method a) compute pairwise distances between sequences
What is Inoculation and Culturing? In microbiology, inoculation is the process where a microbe of interest is introduced into a previously sterilized growth medium for the p
Oxygen Dissociation Curves The oxygen content of blood fully saturated or oxygenated can be calculated. It is known as the oxygen capacity of blood and this varies for differe
TYPES OF FERTILIZATION - On the basis of site of fertilization, it is of two types - 1. External fertilization 2. Internal fertilization 1 . EXTERNAL FERTILIZ
Structural classification of bone Macroscopically, bone tissue can be classified into two types, compact and trabecular bone. Compact bone is dense, corticated and makes up the
How are amino acids brought to the cellular site where translation takes place? What is an anticodon? Amino acids are brought to ribosomes by RNA molecules called as transfer R
Describe Congenital Pulmonary Stenosis? The murmur present since birth. PS may be valvular, sub-valvular, or supravalvular. An obstruction may occur within the RV cavity by an
Alteration of Turgor of Guard Cells There are two ways in which the relative turgor of guard cells may be altered. A decrease in osmotic potential or A decre
Explain the History of Plant Classification? Before Darwin's theory of evolution and publication of his epoch making work 'Origin of Species' in 1959 no outstanding basis for
Define Regulation of Water Balance? The input of water, as well as, its loss can be highly variable due to individual habits and environmental factors; in spite of this, the to
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