Explain lipid formulations, Biology

Assignment Help:

Explain Lipid Formulations

Three lipid formulations of amphotericin B are marketed in the US: amphotericin B lipid complex (ABLC, Abelcet), liposomal amphotericin B (L-AmB, AmBisome), and amphotericin B colloidal dispersion (ABCD, Amphotec). In clinical trials, these formulations have been at least as effective as amphotericin B deoxycholate.

Compared to conventional amphotericin B, acute infusion-related reactions are worse with Amphotec, less with  Abelcet, and least with AmBisome.  Nephrotoxicity is less common with lipid-based products and, when it occurs, less severe than with amphotericin B deoxycholate. Liver toxicity, which is generally not associated with amphotericin B deoxycholate, has been reported with the lipid formulations

 


Related Discussions:- Explain lipid formulations

What are some examples of biological activities, Q. What are some examples ...

Q. What are some examples of biological activities in which osmosis plays an significant role? Hemolysis destruction of red blood cells by entrance of water, the hydric regulat

What is sodium-potassium pump, Sodium-potassium pump A. The net flux of...

Sodium-potassium pump A. The net flux of sodium is from a region of high sodium concentration to a region of low sodium concentration. B. The net flux of potassium is from a

Aortic valve replacement-types of surgery in ar, Aortic Valve Repla...

Aortic Valve Replacement :  Technique: Surgical technique is not much different from what has already been described for aortic stenosis. Care must be taken to avoid VF

Illustrate about sarcoplasmic reticulum membranes, An increase in the calci...

An increase in the calcium conductance of all sarcoplasmic reticulum membranes of a skeletal muscle with no external forces on it leads to A. Increased binding of calcium ions

What is the probability the child will have pku, PKU is a recessive disorde...

PKU is a recessive disorder. Suppose two people who were heterozygous for PKU married and had a child. What is the probability that the child will have PKU?

Difference between rough and smooth endoplasmic reticulum, Q. What is the d...

Q. What is the difference between rough and smooth endoplasmic reticulum? The endoplasmic reticulum is a delicate membranous structure contiguous to the nuclear membrane as wel

Why the av node of a mammalian heart is destroyed, The AV node of a mammali...

The AV node of a mammalian heart is destroyed. A. A depolarization in a cell in the left atrium will cause a depolarization of a cell in the left ventricle. B. The contracti

Pporifera, write the general account of porifera

write the general account of porifera

How does chewing food help to speed up digestion, How does chewing food hel...

How does chewing food help to speed up digestion? Chewing reduces food to portions small sufficient to be swallowed and enhances the surface area of the food for digestive enzy

What is bilateral symmetry system, What is Bilateral Symmetry system? T...

What is Bilateral Symmetry system? To review: all animals besides the sponges (Phylum Porifera) belong to the Eumetazoa. There are two groups within the Eumetazoa that possess

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd