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Explain Itraconazole
It has a broader spectrum of activity than fluconazole. It is active against a wide variety of fungi including Cryptococcus neoformans, Aspergillus spp., Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, Paracoccidioides brasiliensis, Pseudallescheria boydii, Sporothrix spp., and dermatophytes. It also has good activity against most Candida spp. containing some strains of fluconazole-resistant C. glabrata. Itraconazole has no clinically meaningful activity against Fusarium spp. or Zygomycetes. Itraconazole is not recommended for treatment of meningitis because it does not cross the blood-brain barrier.
Q. Explain the Bone Implant Interface? Three phases have been described in the development of bone implant interface. 1. Stabilization phase Subendosteal and subperiost
(1) It should have high "calorific value" or heat content. (2) It should have "moderate ignition temperature". (lgnition temperature is the minimum temperature at which it s
Explain about the Multiple Sclerosis This is a disease characterised by the loss of myelin, largely in motor tracts but also in sensory tracts. The loss of myelin is not unifor
Liver function test should be done for all diabetic patients. This will help the doctor in the choice of drugs for the treatment of diabetes since liver abnormalities influence the
What are main limitations on size that can be synthesized and how will that be change over next few years? A: Today, a 10kb gene or longer is built as part of the regular produ
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Q. What is Acid cleaning compounds? Acid-based cleaners like phosphoric acid and hydrofluoric acid are commonly used. They are very useful in removing minimal scales that
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Define Reagents for Estimation of Calcium Using EDTA Titrimetric Method? 1. Buffer solution: Dissolve 16.9 g NH 4 CI in 143 ml NH 4 OH. To this add 50 ml of solution containing
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