Explain inotropes and vasopressors, Biology

Assignment Help:

Explain Inotropes and Vasopressors

Persisting hemodynamic instability after correction of hypovolemia would necessitate the use of vasoactive agents. Which drug or intervention to use would depend on the type of shock. The clinical effects of available drugs are summarized in table. In cardiogenic shock, characterised by low cardiac output and peripheral vasoconstriction, dobutamine is a good drug to use, as it has inotropic as well as vasodilator effect. Phosphodiesterase inhibitors like milrinone also act in a similar fashion. Pure vasodilators like glyceryl trinitrate and sodium nitroprusside may also help in reducing the peripheral vasoconstriction and thereby, the systemic vascular resistance. Intra-aortic balloon counterpulsation increases coronary blood flow and reduces left ventricular afterload, thus reversing myocardial ischemia and improving cardiac performance. It is useful in patients in whom myocardial revascularization can be accomplished either by surgery or angioplasty and in the postoperative cardiac surgical patient with low cardiac output state. It is less successful in acute myocardial infarction complicated by cardiogenic shock if there is no lesion that can be revscularized.

531_summary of clinical effect.png


Related Discussions:- Explain inotropes and vasopressors

What are plasmids, What are plasmids? Plasmids are circular DNA molecul...

What are plasmids? Plasmids are circular DNA molecules there in the genetic material of some bacteria. They might be containing genes responsible for bacterial resistance to so

Role of psychiatric nurse, ROLE OF PSYCHIATRIC NURSE: In Blocks 2 and ...

ROLE OF PSYCHIATRIC NURSE: In Blocks 2 and 3 you have learnt about various therapeutic interventions  for mental disorders  like anxiety neurotic disorders, psychotic disorder

What are toxic effects of lectins or haemagglutinins, What are toxic effect...

What are toxic effects of lectins or haemagglutinins? Well, these can cause growth inhibition in animals and diarrhoea, nausea, bloating and vomiting in case of human beings. W

Functions of pantothenic and biotin acid for the body, Q. What are the func...

Q. What are the functions of pantothenic and biotin acid for the body? How are these vitamins obtained? Biotin also known as vitamin B8 is a vitamin that acts in the metabolism

Knotted network of capillaries, A knotted network of capillaries within a n...

A knotted network of capillaries within a nephron, the glomerulus, receives arterial blood and is porous enough to allow much of the fluid portion of the blood to flow out of it al

Pasteurellosis, Pasteurellosis Haemorrhagic septicaemia (HS) Synonym  ...

Pasteurellosis Haemorrhagic septicaemia (HS) Synonym    :    Gal Ghotu Causative organism B:2                              :    Pasteurella multocida Serotype Haemorrhage sept

Beta decay, Beta decay  is the type of radioactive decay in which the radio...

Beta decay  is the type of radioactive decay in which the radioisotope emits a little negatively-charged and fast-moving particle from its nucleus. A beta particle is almost simila

Problem with role of lymphatic system, Normal 0 false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Does ph affect the enzyme activity, Q. Does pH affect the enzyme activity? ...

Q. Does pH affect the enzyme activity? The concentrations of hydrogen ions in solution affect the enzyme activity. Each enzyme has utmost efficiency under an optimum p H . S

Illustrate fluoxetine is an antidepressant drug or not, Fluoxetine is an an...

Fluoxetine is an antidepressant drug that presents an action mechanism related to the synaptic transmission. What is that mechanism? Fluoxetine is a substance that inhibits th

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd