Explain inotropes and vasopressors, Biology

Assignment Help:

Explain Inotropes and Vasopressors

Persisting hemodynamic instability after correction of hypovolemia would necessitate the use of vasoactive agents. Which drug or intervention to use would depend on the type of shock. The clinical effects of available drugs are summarized in table. In cardiogenic shock, characterised by low cardiac output and peripheral vasoconstriction, dobutamine is a good drug to use, as it has inotropic as well as vasodilator effect. Phosphodiesterase inhibitors like milrinone also act in a similar fashion. Pure vasodilators like glyceryl trinitrate and sodium nitroprusside may also help in reducing the peripheral vasoconstriction and thereby, the systemic vascular resistance. Intra-aortic balloon counterpulsation increases coronary blood flow and reduces left ventricular afterload, thus reversing myocardial ischemia and improving cardiac performance. It is useful in patients in whom myocardial revascularization can be accomplished either by surgery or angioplasty and in the postoperative cardiac surgical patient with low cardiac output state. It is less successful in acute myocardial infarction complicated by cardiogenic shock if there is no lesion that can be revscularized.

531_summary of clinical effect.png


Related Discussions:- Explain inotropes and vasopressors

How dissimilar are intracellular and extracellular digestion, How dissimila...

How dissimilar are intracellular and extracellular digestion? What is the evolutionary benefit of extracellular digestion? Intracellular digestion is that in which the breaking

Theoretical foundation of halsted reitan battery, Theoretical Foundation of...

Theoretical Foundation of Halsted Reitan battery There are really two theoretical bases for the Halsted Reitan battery, one contained in brain and intelligence and related writ

Indications for surgery-pericardial diseases, Indications for Surgery :  O...

Indications for Surgery :  Once diagnosis of constrictive pericarditis is made and confirmed by chest X-ray, ECG, echocardiogram, CT, MRI scan, cardiac catheterisation and angio,

Cilia and flagella – protozoans, Cilia and Flagella – Protozoans Cilia...

Cilia and Flagella – Protozoans Cilia and flagella basically have a similar structure and distinction between the two on structural basis does not exist. There is a filament o

Risk analysis - definition of hazard, Risk analysis - Definition of Hazard ...

Risk analysis - Definition of Hazard Hazard   :  A  biological, chemical  or  physical  agent  in or property  of food that might be have an adverse health effect.

Development of ovule, Development of Ovule The ovule develops from a s...

Development of Ovule The ovule develops from a specialised region of the ovary - the placenta. Initially it appears as a small mound on the placenta, and is composed of homoge

Types of stem cells-pulp tissue revascularization, Embryonic stem cells: c...

Embryonic stem cells: can differentiate into all cell types of the specialized embryonic tissues when given sufficient and necessary stimulation for a specific cell type, e.g. Plu

Zoology, classification mollusca

classification mollusca

Explain precautions for performing completed coliform test, Explain Precaut...

Explain Precautions for Performing the Completed Coliform Test 1. Aseptic conditions should be adopted while performing the experiment. 2. Destaining is the critical step in

Explain sodium alginate, Explain Sodium alginate Sodium alginate helps ...

Explain Sodium alginate Sodium alginate helps in aiding cloud retention and inhibits clarification in orange squash and crush. It has been used as the most efficient stabilizer

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd