Explain Development of Agranulocytes

Agranulocytes, we know, are the monocytes and lymphocytes. Agranulocytes develop in the bone marrow and thymus. They start as stem cells. They are primary lymphoid organs where pluripotent stem cells (cells which cannot grow into a whole organism) form lymphoblasts. They proliferate and differentiate into immature lymphocytes. The ones which mature in bone marrow are called B-lymphocytes. Another group which matures in the thymus is called T-lymphocytes. These lymphocytes travel to secondary lymphoid organs such as lymph nodes and spleen, where lymphopoiesis continues. They become unique among blood cells since their production is not limited to bone marrow alone.

With this, we end our discussion on development and regulation of leukocytes. We shall end our study of the immune system by presenting a review about the antigen-antibody relationship and the various methods of their in-vitro detection.