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Adverse Effects of Valacyclovir
Valacyclovir is generally well tolerated; adverse effects are similar to those with acyclovir. GI disturbance, headache, rash, CNS effects such as hallucinations and confusion, and nephrotoxicity can occur. A thrombotic thrombocytopenic purpura/hemolytic uremic syndrome has been reported in some severely immunocompromised patients taking high doses.
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