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What are the situations in which the environment can change the genotype of an individual? What is the condition for this type of change to be transmitted to the offspring?
The environment can only alter genotypes when its action causes alterations in the genetic material (mutations) of the individual, i.e., deletion, addition or substitution of entire chromosomes or of nucleotides that form the DNA molecules.
Mutations are only transmitted to the offspring when affecting the germ cells that produce gametes or the gametes themselves.
Non-threshold approaches For genetic carcinogenes, the "NOEL-safety factor" approach is generally not considered a suitable method for setting the acceptable intake level
Modalities Available for Sterilization The most accepted methods of sterilization can be classified as follows: Physical Agents: These comprise of: Sunlight Drying
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