Elongation: what is translocation, Biology

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A Complex  of  elongation  factor  EF-G  (also known as  translocase)  and  GTP example for  EF-G/GTP binds  to the  ribosome.  There are three concerted movements  now happen collectively called as translocation;  the deacylated tRNA moves from the P site to the E site, the dipeptidyl-tRNA in the A site shifts to the P site and the ribosome  moves with the mRNA (5' to 3') by three nucleotides to place the next codon in the A site. In during the translocation events the GTP is hydrolyzed to GDP and inorganic phosphate and EF-G is released ready to bind more GTP for another round of elongation.

 


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