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A term which covers the large number of techniques for the analysis of the multivariate data which have in common the aim to assess whether or not the set of variables distinguish or discriminate between the two or more groups of the individuals. In medicine, for instance, this type of methods are generally applied to the problem of using optimally the results from the various tests or the observations of various symptoms to make the diagnosis which can only be confirmed perhaps by the post-mortem examination. In the two group case the mainly used method is Fisher's linear discriminant function, in which a linear function of variables giving the maximal separation between the groups is then determined. This results in the classification rule which may be used to assign the new patient to one of the two groups. The derivation of the linear function supposes that the variance-covariance matrices of the two groups are the same. If they are not then a quadratic discriminant function might be essential to distinguish between the groups. Such a function comprises of powers and cross-products of variables. The sample of the observations from which the discriminant function is derived is commonly known as the training set. When more than two groups are involved then it is possible to determine the several linear functions of the variables for separating them. In common the number of such functions which can be derived is the smaller of q and g-1 where q is the number of variables and g is the number of groups. The collection of the linear functions for discrimination is called as canonical discriminant functions or simply as canonical variates.
Ha: If hyperlipidemia is believed to be a side effect of second-generation antipsychotics (SGAs), then Hispanic patients with SGAs treatment will have the higher frequency of devel
Higher criticism is a multiple-comparison test concept arising from the situation where there are number of independent tests of significance and interest lies in the rejecting jo
Misspecification is the term is applied to describe the assumed statistical models which are incorrect for one of the several of reasons, for instance, using the wrong probability
Confidence profile method : A Bayesian approach to meta-analysis in which the information in each piece of the evidence is captured in the likelihood function which is then used al
Minimization is the method or technique for allocating patients to the treatments in clinical trials which is usually the acceptable alternative to random allocation. The procedur
The functions of the data and the parameters of interest which can be brought in use to conduct inference about the parameters when full distribution of the observations is unknown
Last observation carried forward is a technique for replacing the observations of the patients who drop out of the clinical trial carried out over a time period. It consists of su
Cohort component method : A broadly used method or technique of forecasting the age- and sex-speci?c population to the upcoming years, in which the initial population is strati?ed
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