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A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.
How does the universality of the genetic code make the recombinant DNA technology possible? The universality of the genetic code refers to the fact that all living beings have
Dominance In each community, a few over topping species are present in greater bulk. By their greater number or biomass (living weight) the dominant species modify the habitat
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PETHIDIN E - Meperidine hydrochloride. Widely used as narcotic analgesic. It has local anesthetic action. METHADON E - It is an orally effective anal
Q Identify truly exciting problem areas in integrative and environmental biology that need an integrated approach utilizing mathematics and statistics. What questions absolutely n
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Q. Explain Spray-dried milk powder? The milk which is concentrated by the process of spray drying contains about 40- 45% total solids. Do you know how the dried milk powder i
Describe TR Murmur and VSD murmur in details? TR Murmur : Characteristic: Holosystolic murmur, loudest at left lower-sternal border and becomes louder with inspiration (Carv
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