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A protein that is normally a single-pass transmembrane protein is absent from the cell surface of the mutant cell line YTM-15. When labeled so that the protein can be localized, you find that this protein is now secreted by the cell. Analysis of the amino acid sequence of the transmembrane protein in question reveals sequence changes that could lead to the observed phenotype. The amino acid substitutions lead to alterations in the ER signal sequence and the stop-transfer sequence. In addition, YTM-15 cells exhibit a point mutation in the gene encoding signal peptidase. Only one mutation is consistent with the observed phenotype. What is the underlying cause of the mutant trait? Explain your reasoning.
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Q. Dietary management of dyspepsia? Keeping in mind the etiology, symptoms and complications of dyspepsia it must be clear that treatment and management of [his disorder does n
Retained foetal membranes The foetal membranes are normally expelled within 6to 12 hr after parturition in cows and buffaloes. If the foetal membranes are not voided even upto
PHOTOTHERAPHY AND EXCHANGE TRANSFUSION: This section will enable you to acquire skills related to phototherapy and exchange transfusion. You will also review the indication
Amniocentesis is a way of prenatal testing in which the amniotic fluid is withdrawn from the uterus by the help of a needle. The fluid and the fetal cells it contains are analyzed
Downer cow syndrome This syndrome is a common sequel to milk fever. The term is commonly applied to those hypocalcaemic cows that remain recumbent for several hours before bein
A decrease in blood plasma levels of parathyroid hormone A. occurs in response to an increase in the levels of calcium ions in blood plasma. B. leads to an increase in the a
A plant grown from one of Mendel's yellow peas is selfed. Five progeny peas are obtained from this self and they are all yellow. If the original selfed plant had been homozygous, w
E n z y m e - linked immunosorbent assay (ELISA): ELISA in its var io us modifications e.g. plate ELISA, sandwich ELISA, competitive ELISA, ELISA strip or
Role of Biotic Factors Inducing Senescence Besides environmental and endogenous factors, biotic factors also play a role in inducing senescence. For example, due to an attack
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