Define regulation of intracellular ca concentration, Biology

Assignment Help:

Define Regulation of intracellular Ca concentration?

The cytoplasmic calcium concentration is regulated by a series of calcium pumps, which either concentrate calcium ions within the intracellular storage sites or extrude them from the cells (where they flow in by diffusion). The physiology of calcium metabolism is primarily directed towards the maintenance of the concentration of ionized calcium in the ECF. This concentration is protected and maintained by a feedback loop through calcium receptors in the parathyroid glands, which control the secretion of parathyroid hormone.

This hormone increases the renal tubular re-absorption of calcium, promotes intestinal calcium absorption by stimulating the renal production of 1,25-dihydroxyvitamin D or calcitriol [1,25- (OH)2D], and, if necessary, resorbs bone. However, the integrity of the system depends critically on vitamin D status; if there is a deficiency of vitamin D, the loss of its calcaemic action leads to a decrease in the ionized calcium and secondary hyperparathyroidism and hypophosphataemia. This is why experimental vitamin D deficiency results in rickets and osteomalacia whereas calcium deficiency gives rise to osteoporosis.

 


Related Discussions:- Define regulation of intracellular ca concentration

Explain in brief about baby blues, Regarding the article "Baby Blues" which...

Regarding the article "Baby Blues" which of the following is a false statement? A. Children, whose mothers underwent severe stressful episodes during pregnancy, have higher tha

What are the final energetic products of each krebs cycle, What are the fin...

What are the final energetic products of each round of the Krebs cycle? Where is most part of the utile energy at the end of Krebs cycle found? After each round of the Krebs cy

Photosynthesis, Aim: To prove that oxygen is evolved during photosynthesis....

Aim: To prove that oxygen is evolved during photosynthesis. Apparatus: Beaker, funnel, test tube, water, Hydrilla plants. Procedure: Take a few pieces of Hydrilla plant. Keep a

Phylum, Are protozoan''s diploblastic or triploblastic

Are protozoan''s diploblastic or triploblastic

Invertibreats, genral charecter and classificatin of porifera

genral charecter and classificatin of porifera

Duration limit of the qrs, Q. Duration limit of the QRS? The duration o...

Q. Duration limit of the QRS? The duration of the QRS is usually reduced slightly during exercise. Because catecholamines increase conduction velocity in the Purkinje fibers an

Determine the stages of healing events, Determine the stages of healing eve...

Determine the stages of healing events The healing events are described in 3 stages Stage 1: Wound healing and formation of woven bone (callus) (2 to 6 weeks) Stage 2: La

Pathogenesis, Even though association between GAS pharyngitis and the ARF i...

Even though association between GAS pharyngitis and the ARF is fairly well established, the exact pathogenic mechanisms are not clearly understood. However, two mechanisms are post

Determine the modification of food starches, Modification of Food Starches ...

Modification of Food Starches Positive attributes of starches can be greatly improved and/or negative characteristics diminished by slight and relatively simple modifications.

Why nutrition is important for health, Why Nutrition is important for healt...

Why Nutrition is important for health Nutrition is one of the basic components of  life. It is an essential part of health care. You already know that good nutrition  is essent

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd