Define Itraconazole

Itraconazole is FDA-approved for treatment of blastomycosis, histoplasmosis (non-meningeal) and aspergillosis in patients who are intolerant of or refractory to amphotericin B. It is also shown for empiric therapy of febrile neutropenic patients with suspected fungal infections. The oral solution is approved for treatment of oropharyngeal and esophageal candidiasis and might have an additional benefit as a topical treatment of this disease. Itraconazole capsules are approved for treatment of finger nail and toenail onychomycosis because of dermatophytes.