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Q. Define Diabetic Ketoacidosis?
Diabetic Ketoacidosis (DKA) is one of the acute complications of diabetes mellitus. The name itself implies that there is acidosis (decrease in blood PH) caused by increased level of ketones in the blood, produced because of less insulin. It is more common in Type 1 DM, as Type 1 DM is associated with absolute insulin deficiency. However, in Type 2 DM too, where there is only relative insulin deficiency, diabetic Ketoacidosis (DKA) can be seen.
Unlike DNA binding domains and dimerization domains, no general structural motifs have since been identified in the activation domains of diverse transcription factors.
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