Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Define about Iodine Metabolism?
Now, we will very briefly study how iodine is absorbed, distributed in the body and ' excreted out. Like other nutrients, dietary iodide is either found free or bound to amino acids. It is primarily found as iodide or iodate. The latter form is reduced to iodide by glutathione in the gut. Iodide is rapidly 'and completely absorbed throughout the gastrointestinal tract and very little iodine appears in faeces. Iodine bound to amino acids is also absorbed but less efficiently. The thyroid hormones: thyroxine (T4) and triiodothyronine (T3) are also absorbed unaltered. Therefore, T4 medication can be administered orally.
After absorption, free iodide appears in the blood and circulates to all tissues. Thyroid gland traps most of the ingested iodide (80%). This is achieved against an iodide gradient (often 40 to 50 times plasma concentration) by sodium-dependent active transport system. This mechanism is regulated by thyroid stimulating hormone (TSN) secreted by pituitary. Thyroid takes up almost 120 mcg of iodide per day. Other tissues such as salivary glands, gastric mucosa, choroid plexus and mammary glands also concentrate the element by a similar active mechanism. Several sulphur-containing compounds such as thiocyanate, isothiocyanate and goitrill inhibit active transport mechanism by competing for uptake with iodide. Thus, iodide uptake by thyroid gland may be reduced. These are called goitrogens and their goitrogenic activity can be overcome by iodine supplementation.
Ventricular Septal Defect (VSD) In ventricular septal defect there is abnormal communication between right and left ventricle. Anatomically 90 per cent of all VSD are located
What do you understand by Heterotrophic? Organisms which are not capable of converting light into chemical energy. They should consume other organisms or material produced by o
What is the proper name for EDTA and what is it? EDTA is ethylenediamine tetraacetic acid. It is a tough chelating agent. It has many uses containing: 1) Industrial cleaning
What is linkage? Two genes are said to be under linkage, or linked, when they reside in the same chromosome. For instance, the research of the human genome discovered that t
A healthy person is on a diet that having of very small amounts of water. A. This person will make a large volume of dilute urine with low amounts of dissolved solutes. B. T
What do you mean by Cold Deserts? Cold deserts cover a vast area north of the Himalayan ranges forming an ecosystem with exceptionally low temperatures which may reach - 75°C a
Irritability If a bright torch of light is flashed across your eyes, you close your eyes instinctively. The bright light acts as a stimulus (pl, stimuli) and closing your eyes
Define Preterm and Low Birth Weight? The foetal and neonatal health is mainly dependent on the birth weight and it has been well recognized that perinatal (from birth upto one
A genetic trait which is considered to be harmful in the present day might prove to be beneficial in future. For example by removing the trait for sickle cell we may increase the s
Q. Proteins requirement in dyslipidemia? Proteins: While the quantity of protein does not impose any significant impact on the serum lipoproteins, it is the quality of protein,
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +91-977-207-8620
Phone: +91-977-207-8620
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd