Define about iodine metabolism, Biology

Assignment Help:

Define about Iodine Metabolism?

Now, we will very briefly study how iodine is absorbed, distributed in the body and ' excreted out. Like other nutrients, dietary iodide is either found free or bound to amino acids. It is primarily found as iodide or iodate. The latter form is reduced to iodide by glutathione in the gut. Iodide is rapidly 'and completely absorbed throughout the gastrointestinal tract and very little iodine appears in faeces. Iodine bound to amino acids is also absorbed but less efficiently. The thyroid hormones: thyroxine (T4) and triiodothyronine (T3) are also absorbed unaltered. Therefore, T4 medication can be administered orally.

After absorption, free iodide appears in the blood and circulates to all tissues. Thyroid gland traps most of the ingested iodide (80%). This is achieved against an iodide gradient (often 40 to 50 times plasma concentration) by sodium-dependent active transport system. This mechanism is regulated by thyroid stimulating hormone (TSN) secreted by pituitary. Thyroid takes up almost 120 mcg of iodide per day. Other tissues such as salivary glands, gastric mucosa, choroid plexus and mammary glands also concentrate the element by a similar active mechanism. Several sulphur-containing compounds such as thiocyanate, isothiocyanate and goitrill inhibit active transport mechanism by competing for uptake with iodide. Thus, iodide uptake by thyroid gland may be reduced. These are called goitrogens and their goitrogenic activity can be overcome by iodine supplementation.


Related Discussions:- Define about iodine metabolism

Desscribe formation of sperm cells from germ cells, Q. Indicating the name ...

Q. Indicating the name and respective ploidy of each involved cell how can the formation of sperm cells from germ cells be described? The formation of spermatogenesis or sperm

Explain normal nutrition - a base of therapeutic diet, Normal nutrition: a ...

Normal nutrition: a base of therapeutic diet Normal nutrition is the foundation upon which the  therapeutic modifications are based. The primary principle of diet nutrition the

Describe fruit in which seed attached to one ovary wall, Which of the below...

Which of the below describes the type of fruit characterized as a dry, simple, one-seeded indehiscent (pron: in-deh-HISS-ent) fruit with seed attached to one ovary wall at only one

Define obligatory and facultative water excretion, Define Obligatory and Fa...

Define Obligatory and Facultative water excretion? i) Obligatory water excretion: The kidney is 'obligated' to excrete some water to rid the body of its daily load of urinary s

What are organic chemical groups that divide carbohydrates, What are the or...

What are the organic chemical groups that characterize carbohydrates? How are carbohydrates classified according to the presence of those groups? Carbohydrates are also called

Reproduction, briefly deccribe the eggs snd follicles

briefly deccribe the eggs snd follicles

How factors affecting energy expended in physical activity, How Factors Aff...

How Factors Affecting Energy Expended in Physical Activity? Physical activity as we learnt earlier is the second largest component of daily energy expenditure, after BMR. Howev

What is tricuspid atresia: surgery for single ventricle, What is Tricuspid ...

What is Tricuspid Atresia: Surgery for Single Ventricle Physiology In tricuspid atresia, the right atrium fails to open into right ventricle through a right atrioventricular va

Protozoa, disadvantages of protozoa in points

disadvantages of protozoa in points

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd