Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Define alcoholic cardiomyopathy, Q. Define Alcoholic Cardiomyopathy? In...

Q. Define Alcoholic Cardiomyopathy? In a case of dilated cardiomyopathy alcohol cardiomyopathy is suspected if there is history of alcohol intake of 100g/day for more than 10

Define in brief about the term - mri, Define in brief about the term - MRI ...

Define in brief about the term - MRI MRI is a more recent development that was initially introduced as a rival to CT. The technique itself is complex, relying on measurement o

Theskin, drawandlabelthemajorendocrineglandsofthehumanbody

drawandlabelthemajorendocrineglandsofthehumanbody

What are the uses of construction of a retaining wall, What are the uses of...

What are the uses of construction of a retaining wall? The retaining wall is constructed whenever space requirement do not allow the natural slope to be formed for an excavatio

Digestive system, identify structural modifiactions of the stomach and smal...

identify structural modifiactions of the stomach and small intestine walls that enhance the digestive processes in these regions

Explain the drug effects on nutritional status, Explain the Drug Effects on...

Explain the Drug Effects on Nutritional Status? Drugs can affect nutritional status in a number of ways i.e. by enhancing excretion of certain nutrients, by interfering with nu

Normal pattern reappears, During the course of a physiology laboratory, a s...

During the course of a physiology laboratory, a student finds that her PR interval is 0.24 second. Concerned, she takes her own ECG again an hour later and sees an area of the ECG

How does the breathing process correct alkalosis, Q. How does the breathing...

Q. How does the breathing process correct alkalosis? If the body undergoes alkalosis the respiratory center located in the medulla gets the information and induces the lowering

How the average number of offspring raised to adulthood, Researchers (Helle...

Researchers (Helle et al., 2004) analyzed rates of twin births in the Sami population of Northern Scandinavia during the eighteenth and nineteenth centuries. They found that (1) a

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd