Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Isolated fibre required for diabetes patient, Q. Isolated fibre required fo...

Q. Isolated fibre required for diabetes patient? Isolated fibre: It is generally recommended that diabetics should substitute whole wheat flour with soya flour, whole Bengal f

Llustrate the role of each area in the evolution of the hebe, llustrate the...

llustrate the role of each area in the evolution of the Hebe Uses appropriate examples from the Hebe data to illustrate the role of each area/concept in the evolution of the He

What do you determine by atriopore, What do you determine by Atriopore? ...

What do you determine by Atriopore? The external opening to atrium. In cephalochordates water passes across pharyngeal slits into atrium and from there leaves through atriopore

Importance of biodiversity, T hese are some important uses of biodiversity....

T hese are some important uses of biodiversity. 1.   Source of food, medicines and drugs: (a)       Wheat, rice and maize are three carbohydrate rich crops and contribute

What is the life cycle of trypanosoma cruzi, What is the life cycle of Tryp...

What is the life cycle of Trypanosoma cruzi? Trypanosoma cruzi is a heteroxenous parasite, i.e., it has an intermediate host, the triatomine bug, and an ultimate host, the hum

State the number of nuclear dna molecules, For each of the following stages...

For each of the following stages, state the number of nuclear DNA molecules in one of your cells (i.e., 23,46, or...) and its ploidy (i.e.,n, 2n, or...). 1.) Prophase of mitosis

What is portal and rental circulation, What is Portal and Rental Circulatio...

What is Portal and Rental Circulation ? The body has other circulation systems that do not return blood directly to the heart. For instance, the blood that drains from the abdo

Nervous system and nerve cells, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE

Stentless devices -biological valves, Stentless Devices : A bioprosthesis...

Stentless Devices : A bioprosthesis mounted on a stent reduces the effective orifice area (EOA). The newer version (third generation) stentless gluteraldehyde preserved porcine v

Risk factor modification, Risk Factor Modification :  Even after CABG,...

Risk Factor Modification :  Even after CABG, patients are at risk of progression of native coronary artery disease and development of lesions in the conduits. Modification of

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd