Chromosome jumping, Biology

Assignment Help:

Chromosome jumping is the technique whereby one begins with a piece of DNA from one area of a chromosome, and obtains clones from nearby areas without cloning everything in between (as in chromosome walking). One round of jumping yields the new clones at the distances of several tens of kb away from the beginning point. In practice, this method is used when classical genetics proves that a known piece of DNA is located on the chromosome close to the gene you would like to clone (like a human disease gene). By cloning the fragments some distance away in both the directions from the known fragment, one might attain 
(1) fragments further from the required gene (which are discarded); 
(2) the fragments are even more closely linked to the required gene (in which case one goes for another round of jumping); or 
(3) fragments from within required gene - the optimal result. 


Related Discussions:- Chromosome jumping

Parenchymal inflammation, Parenchymal Inflammation Parenchymal inflamm...

Parenchymal Inflammation Parenchymal inflammation can be due to infectious diseases or acute bronchitis or pneumonia discussion will be mainly on pneumania in the following t

What is the emperical evaluation, What is the Emperical evaluation Emp...

What is the Emperical evaluation Emperical evaluation based on: i) Time elapsed since stage one surgery - Considering the sigma cycle of bone formation in humans, a time pe

Explain foscarnet, Foscarnet  (Foscavir)  Foscarnet is an alternative t...

Foscarnet  (Foscavir)  Foscarnet is an alternative to ganciclovir and valganciclovir for treatment of CMV infection. It is approved for use in CMV retinitis, including progress

Structure of the human vision apparatus, Q. What are the structures that co...

Q. What are the structures that compose the human vision apparatus? The organs of the human visual apparatus are the eyes the optical nerves and the visual areas of the brain l

Embrylogical devlopment of hypospadias, Embrylogical Devlopment of Hypos...

Embrylogical Devlopment of Hypospadias The development of the penis and scrotum is intluenced by the testes. In the absence of the testes, the female structures of the

The main causes of the loss of biological diversity, What are the main caus...

What are the main causes of the loss of biological diversity nowadays? The biggest dangers to biological diversity today are the action of humans. The most of them is the destr

Define types of root canal perforations according to causes, Define Types o...

Define Types of Root Canal Perforations According To Causes Iatrogenic causes. Pathological causes.

Explain stem cell therapy, Stem Cell Stem cell therapy could enable ind...

Stem Cell Stem cell therapy could enable individuals to survive and contribute their alleles to the gene pool who might not have already done so thus increasing genetic diversi

Deficiency diseases-iodine deficiency, Iodine  deficiency Iodine is an...

Iodine  deficiency Iodine is an important component of thyroid hormones, which play active role in several physiological process such as control of basal metabolic rate, oxidat

Define about the paper chromatography, Define about the Paper Chromatograph...

Define about the Paper Chromatography? Paper chromatography is a very useful technique for separating mixtures of metal ions, anions, amino acids, sugars, dyes, drugs, etc. The

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd