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In animals, some of bacteria and fungi, and the first step in tetrapyrrole synthesis is the condensation of the amino acid glycine with succinyl CoA (an intermediate of the citric acid cycle) to built ALA (aminolaevulinic acid). This reaction is catalyzed by the enzyme ALA synthase that needed the coenzyme pyridoxal phosphate and is situated in the mitochondria of eukaryotes. This committed phase in the pathway is subject to regulation. Synthesis of the ALA synthase is feedback-inhibited by heme. In algae, plants and various bacteria there is an alternative route for ALA synthesis which have the conversion of the intact five-carbon skeleton of glutamate in a series of three steps to yield ALA. In all organisms there are two molecules of ALA then condensing to form porphobilinogen in a reaction catalyzed by ALA dehydratase (also called as porphobilinogen synthase). Inhibition of this enzyme by lead is one of the main manifestations of acute lead poisoning.
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Determine the use of natural colourants The use of natural colourants is limited due to their instability, low tinctorial power or price disadvantage. The trend towards natura
WRITE ON FUNGAL NUTRITION
What are the adaptions flatworms neeed in order to live in their environment?
Factors affecting vitamin utilization Raw soybean contains enzyme lipoxygenase which can be destroyed by heating for 5 min with steam at atmospheric pressure. Lipoxygenase cata
How do the plants classify according to their photoperiodism-based flowering? According to their photoperiodism-based the flowering plants classify as long-day plants, those th
Favus Fowl favus is a superficial, chronic, sporadic mycotic infection of birds caused mainly by Trichophyton gallinae. Very rarely Trichophyton simii is also involved in the
In his experiments, Mendel noted that when two traits are involved in a genetic cross, they are inherited independently of each other. The reason for this is that A. genes on the s
Physical Lay Out: Physical lay out of the nursing unit should be planned and built in such a manner so that it helps the head nurse to discharge her duties/carry out her resp
The left atrium is a thin walled cavity. Most of the wall is smooth. Musculi pectinati are present only in the auricle of the atrium. The interatrial septum separates the cavity of
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