Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

Define risk management, Define Risk management Risk management is def...

Define Risk management Risk management is defined  for the purposes of the Codex Alimentations Commission as  "the process, distinct from  risk assessment,  of weighing polic

What is genetic mapping, How can the concept of recombination frequency be ...

How can the concept of recombination frequency be used in genetic mapping? Genetic mapping is the determination of the location of the genes in a chromosome. By determining

What is particularly of the mucous membranes, How would carbon monoxide poi...

How would carbon monoxide poisoning affect a person's coloring, particularly of the mucous membranes? How would it affect the hemoglobin concentration, hematocrit, and percent oxyh

Symptoms of malabsorption syndrome, Q. Symptoms of malabsorption syndrome? ...

Q. Symptoms of malabsorption syndrome? The most common symptoms are weakness, lassitude and marked weight loss. Steatorrhoea (excess fat in stools), anaemia and chronic ill h

Development of reserves - conservation of wildlife, Development of Reserves...

Development of Reserves - Conservation of Wildlife Establishment of Biological reserves, National parks, Forest reserves, Wildlife refuges and Biosphere reserves are effective

Ideal characteristics of blood pump-cardio pulmonary bypass, Blood Pump :  ...

Blood Pump :  Ideal Characteristics 1) I should be able to pump up to seven litres of blood per minute. 2) It should not damage cellular and cellular components of blo

Explain the infarct exclusive technique, Explain the Infarct Exclusive Tech...

Explain the Infarct Exclusive Technique? Infarct Exclusive Technique :  Left ventriculotomy is done through the infarcted area. No attempt is made to close the ventricu

Chuck darwin knew blending theory, Chuck Darwin knew BLENDING THEORY, but h...

Chuck Darwin knew BLENDING THEORY, but he also knew that if it was true his NOT work because

Legal rights of psychiatric patients, LEGAL RIGHTS OF PSYCHIATRIC PATIENTS:...

LEGAL RIGHTS OF PSYCHIATRIC PATIENTS: When a patient is admitted in psychiatric hospital he may be deprived of  the freedom  to leave the hospital, and also to maintain certai

Adaptation, Adaptation is the tendency of an organism to suit its environm...

Adaptation is the tendency of an organism to suit its environment; one of the main points of Charles Darwin's theory of evolution by the natural selection: organisms adapt to thei

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd