Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

Compound feed prepration, Compound feed prepration The compounding of anim...

Compound feed prepration The compounding of animal feed involves processing and blending of raw feed ingredients of wide ranging physical, chemical and nutritional composition int

How nutritional status affects the bmr, How Nutritional status affects the ...

How Nutritional status affects the BMR? Under nutrition and starvation are the factors which require consideration. Prolonged under nutrition or starvation causes a reduction o

Phylum Echinodermata, define and explain Water vascular system with podia a...

define and explain Water vascular system with podia and tube-feet madreporite mostly present

Non-consumptive value, This is concerned more with nature's services which ...

This is concerned more with nature's services which also make vital contributions to the welfare of society and to ecological processes without which our planet would be uninhabita

Shrub stage - xerarch, Shrub Stage - Xerarch Sufficient soil is formed...

Shrub Stage - Xerarch Sufficient soil is formed in the herbs stage, for supporting the woody plants or the shrubs. They migrate with the help of seeds or rhizomes from the adj

Bees, is there a difference between the giant asiatic bees apis dorsata and...

is there a difference between the giant asiatic bees apis dorsata and Philippine giant bees apis breviligula

Factors influencing the supply of health care, Normal 0 false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Agro industrial-potassium, Potassium Potassium, the third most abundan...

Potassium Potassium, the third most abundant mineral in the body, is the major cation in intracellular fluid. Forages are excellent source of potassium, usually containing 1 t

What is an antigen, What is an antigen? Antigen is any substance, parti...

What is an antigen? Antigen is any substance, particle or infectious agent known as foreign to the body. The contact of the antigen with the body promotes a defense reaction ag

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd