Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

State the types of brain trauma, State the types of brain trauma? There...

State the types of brain trauma? There are two main types of brain trauma a) open head injury and b) closed head injury

Are mollusc metameric beings, Q Are mollusc metameric beings? Exclusively a...

Q Are mollusc metameric beings? Exclusively analyzing this feature could it be said that molluscs are evolutionarily proximal to nematodes or to annelids? In molluscs there is

Describe explicit and semantic memory, Q. Describe Explicit and Semantic Me...

Q. Describe Explicit and Semantic Memory? Explicit memory: This is the conscious recollection of information such as specific facts or events and at least in humans that can be

What is pus, What is pus Pus is a residual of the inflammatory reaction...

What is pus Pus is a residual of the inflammatory reaction. It is having a mixture of fragments of dead leukocytes, infectious agents (generally bacteria) and tissues.

Preparation of the laboratory samples, Q. Preparation of the Laboratory Sam...

Q. Preparation of the Laboratory Samples From the primary sample while selecting a representative laboratory sample, we need to consider the following: a) Laboratory sampl

Goal of fostering the integration of biology, Evaluate how best to achieve ...

Evaluate how best to achieve the goal of fostering the integration of biology, statistics, and mathematics. What impediments stand in the way of progress? What is the best way to

Dietary guidelines fur hyperlipidemic patients, Q. Dietary Guidelines fur h...

Q. Dietary Guidelines fur hyperlipidemic patients? • Calories: to maintain ideal body weight. • Carbohydrates should constitute 55-65% of calories with emphasis on • polysacc

What is paediatric clinical literature, What is paediatric clinical literat...

What is paediatric clinical literature The paediatric clinical literature has expanded greatly in its coverage of the wide variety of medical circumstances that can negatively

Events prior to the sperm-egg fusion, Events prior to the Sperm-Egg Fusion ...

Events prior to the Sperm-Egg Fusion In a number of organisms that have been studied, the sperm remain immotile in the testis or in the semen. The sperm become active and mot

Process of stabilize lipoprotein structure, Q. Process of stabilize lipopro...

Q. Process of stabilize lipoprotein structure? Ans. Apoproteins not only stabilize lipoprotein structure but also have other important regulatory functions in lipoprotein

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd