Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

Hypocoagulation disorder and vitamin k deficiency, Which of the following p...

Which of the following patients likely faces the highest risk of an acquired hypocoagulation disorder and vitamin K deficiency? Answer A. A patient who is immunocompromised as a re

Define fat needs in nutrient requirement, Define Fat needs in Nutrient Requ...

Define Fat needs in Nutrient Requirement and Dietary Management? As we have learnt earlier on enteral and parenteral feedings; administration of lipids should be carried out ca

Ctenophora.., Ask queAffinities of ctenophora with platyhelminthesstion #Mi...

Ask queAffinities of ctenophora with platyhelminthesstion #Minimum 100 words accepted#

What is hydrogenqted fat, Q. What is Hydrogenqted Fat? All vanaspati pr...

Q. What is Hydrogenqted Fat? All vanaspati preparations are the result of hydrogenation of oils, where unsaturated fat is converted to saturated fat for its favour and long she

What carbohydrate characteristic chemical features include, Carbohydrate ch...

Carbohydrate characteristic chemical features include: Select one: a. the potential to form multiple hydrogen bonds. b. the existence of one or more asymmetric centers.

Can you explain the lichens, Q. What are the lichens? How fungi participate...

Q. What are the lichens? How fungi participate in this ecological interaction? Lichens are formed by mutualist ecological interaction between algae and fungi or between fungi a

Explain phylum mollusca, Phylum Mollusca (47,000 species) The segmentat...

Phylum Mollusca (47,000 species) The segmentation and coelom may not exist. Diversification through modifications of head, foot; mantle and 'radula for feeding. .Visceralorgans

Explain the working of skeletal muscle, Explain the working of Skeletal Mus...

Explain the working of Skeletal Muscle? Skeletal muscle is under voluntary control and is responsible for voluntary movements of body parts. Skeletal muscle is also called stri

Antibody structure, Antibody Structure: An antibody molecule consist of...

Antibody Structure: An antibody molecule consist of two alike light chains ( 220  amino acids each) ad two similar heavy chains (about  440-450  amino acids each) held together

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd