Angiotensin receptor blockers, Biology

Assignment Help:

Angiotensin receptor blockers block the final common pathway and provide a means of complete blockade of the system.

One of two subtypes of AII receptors, the AT1 receptor produces vasoconstriction and induces muscle cell proliferation when activated; the AT2 receptor produces antiproliferative effects upon activation. Currently available ARBs selectively block the AT1 receptor, producing vasodilatation and inhibiting muscle cell proliferation.

However, these agents do not produce increases in bradykinin, prostaglandins, and nitric oxide in the heart, blood vessels, and other tissues. They   should be considered as alternatives to ACE inhibitors in ACE-intolerant patients especially patients with chronic dry irritating cough and angiedema. Another potential use is to counteract ACE escape, the attenuation of the benefits of ACE inhibition that may occur with time.

Various agents available are losartan, valsartan, irbesartan, candesartan, telmisartan and eprosartan.


Related Discussions:- Angiotensin receptor blockers

Open style - style of stigma interaction, Open Style - Style of Stigma Inte...

Open Style - Style of Stigma Interaction Aegle, Fritillaria, Lilium spp. have variable number of stylar canals depending on the number of carpels. The epidermal cells of styla

Phylum arthropoda, PHYLUM ARTHROPODA Definition and Introduction ...

PHYLUM ARTHROPODA Definition and Introduction Bilateral  and protostomial eucoelomate  eumetazoa with metamerically  segmented  and each  segment bearing a pair  of  join

Animal biodiversity, discuss why obelia is considered to be of special inte...

discuss why obelia is considered to be of special interest in zoology as an animal showing an intermediate grade of organisation

Etiologic factor of diabetes, Q. Etiologic factor of diabetes? The prec...

Q. Etiologic factor of diabetes? The precise etiology of diabetes is not known but multiple factors contribute to the disorder. These are reviewed herewith. Type I Diabetes

Explain the basic concept of proteins, Explain the Basic Concept of Protein...

Explain the Basic Concept of Proteins? Proteins, as we already knows by now are products of amino acids. Each molecule of protein is composed of many molecules of amino acids j

Zoology, Write about 25 parasites of protozoans? And writ the class family ...

Write about 25 parasites of protozoans? And writ the class family and full history about these parasites?

Parts of a typical flower with all its definations , parts of a typical fl...

parts of a typical flower? define its parts and internal parts completely? show complete colourful diagram?

Amino acids, An amino acid is amphiprotic (have both acid and base)  ...

An amino acid is amphiprotic (have both acid and base)              o    Some are polar, non polar, acidic or basic List of amino acids (red are non-polar, yellow are

Explain coronaw artery disease, Explain CORONAW ARTERY DISEASE (CAD)? A...

Explain CORONAW ARTERY DISEASE (CAD)? As far as CAD is concerned the people of South Asian region are at a very disadvantageous position. The term 'South Asians' includes perso

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd