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Myopia, or nearsightedness, is the most common human eye disorder in the world, and is a significant global public health concern. Along with cataract, macular degeneration, infectious disease, and vitamin A deficiency, myopia is one of the most important causes of visual impairment worldwide. Severe or high grade myopia is a leading cause of blindness because of its associated ocular morbidities of retinal detachment, macular choroidal degeneration, premature cataract, and glaucoma. Ample evidence documents the heritability of the nonsyndromic forms of this condition, especially for high grade myopia, commonly referred to as myopic spherical refractive power of 5-6 diopters or higher. Multiple high grade myopia genetic loci have been identified, and confirmatory studies identifying high grade and moderate myopia loci have also occurred. In general, myopia susceptibility genes are unknown with few association studies performed, and without confirmation in other research laboratories or testing of separate patient cohorts.
Write an essay bringing forth the relation between genes and myopia in 7-8 pages.
Paper should have alteast 15 references and should be cited in the essay.
Examples of positive and negative control of transcription can be found in the regulation of expression of the bacterial operons lac and trp. Use these two operon systems to describe the difference between positive and negative regulation.
The recombination frequency between linked genes A and B is 40%; between B and C, 20%; between C and D, 10%; between C and A, 20%; between D and B, 10%. What is the sequence of the genes on the chromosome
The heterozygous phenotype is known as erminette. what is the genotype of for erminette chickens?
q1. in cases of severe iron deficiency cellular respiration cannot proceed usually. disregarding problems related to
Which of the following statements reflect observations and/or inferences upon which Darwin based his ideas about evolution by natural selection?
What is the independent variable, what is the dependent variable and what is one very obvious control variable?
Describe the structural changes that had to happen to support this move and discuss the functional importance of each of these structures to the environmental changes the plants had to face.
A kidney bean shaped eye is produced by a recessive allele [k] on the third chromosome of Drosophila. Orange eye color, called "cardinal" is produced by the recessive allele [cd] on the same chromosome.
To which blood types could the following people donate?
Many patients with glucose 6-phosphatase deficiency have high serum levels of urate, a condition known as Hyperuricemia. Hyperuricemia can be induced by strenuous exercise. Propose a common mechanism that account for these findings.
Shalom Palul contracted with Capi Cabinets, Inc., in August 1999 for new kitchen cabinets made by Holiday Kitchens. The price was $10,900. On Capi's recommendation, Palul hired Barry Burger to install the cabinets for $1,600. Burger finished the job ..
Why are molecules that block oxidative phosphorylation and the electron transfer chain such dangerous ad potentially deadly poisons?
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