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Monogenic obesity is no more common in Pima Indians than in other populations; nor have other gene variants associated with raised susceptibility to obesity been found in Pima populations. Why then, is it said that Pima Indians have a genetic susceptibility to obesity?
Briefly explain the idea of differential centrifugation. What cellular organelles fraction out during each round of centrifugation.
Hypothesis: since the normal substrate for the enzymes is lactose, adding lactose along with ONPG will reduce the rate of yellow color formation.
You are designing a new single-celled organism. Discuss the problems of size, getting molecules like nutrients and wastes in and out, temperature, energy and replication of genetic materials.
Determine how many molecules of methylene blue dye are in a 256-fold dilution of a 0.00025 percent methylene blue dye stock solution?
An amateur horse breeder has acquired four new bay-coloured mares (female horses) with uncertain pedigree. What are the probable genotypes of the mares purchased.
Explain the processes involved in cellular protein synthesis. How would synthesis be affected by intake of an otherwise adequate diet that is very low in glycine or low in tryptophan?
Mice are diploid with 2n=40. Determine how many chromosomes make up the genome and how many chromosomes would you expect to see in a mouse gamete.
A 23 year old begins to lift weights daily, and his muscle enlarge. Inhibition of which of the following intracellular process prevents skeletal muscle hyperplasia in this individual?
Genetic variation in the population of organisms is good; but, sometimes mutations can be harmful or cause genetic disorders.
During the catalytic cycle of pyruvate dehydrogenase, pyruvate becomes covalently attached to a prosthetic group, thiamine pyrophosphate.
How may you use site-directed mutagenesis to determine whether this residue is essential for proton conduction?
What are the chances that the next child of the parents of the siblings in part (a) will be a Type B son or a Type A daughter? (show Punnett square)
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