Why is an action potential conducted in only one direction

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Why is an action potential conducted in only one direction, from an axon hillock to an axon terminal?

The number of voltage-gated ion channels increases along the length of the axon.

The membrane channels upstream are refractory and cannot open.

The channels are progressively easier to open down the length of the axon.

Second messengers activate channels sequentially.

Reference no: EM13121589

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