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Why are most mutations neutral to slightly deleterious? A.Many mutations are likely to be neutral because of the high level of redundancy of the genetic code or because mutations occur in an area of DNA that does not affect protein coding or expression. B. Many mutations are likely to be slightly deleterious because of the similar properties of some amino acids that may only affect function slightly or because the mutation affects expression but not the protein itself. C. The phenotypic effect of many mutations depends on the environment that they occur in, so mutations can be neutral or only slightly affect fitness if the environment compensates for what would otherwise be a strong effect on fitness. D. All of the above.
explain how an action potential, originating at the axon hillock, is propagated along myelinated and nonmyelinated axons.How are graded potentials made
It is commonly reported that up to 50 percent of a cell’s energy budget is spent on protein synthesis. How do you suppose such a measurement might be made?
Discuss in three sentences or less why DNA polymerases alone cannot initiate complementary strand formations.
choose two organisms from two different trophic levels in the marine ecosystem and explain the impact of the algal bloom on their ecology.
he clinical laboratory returns the following arterial blood values for patient: pH = 7.2; plasma HCO3- = 29 mmol/L; plasma pCO2 = 75 mmHg. Determine the patient's acid-base disorder?
If the total free energy of the system X+Y X-Y at 37 C is +6700 J/mol and the total entropy change is -125 J/mol K, what is the total enthalpy change? Also, is the problem endothermic or exothermic and endergonic or exergonic.
As a 1st step towards cloning the ding-dong gene from Drosophila, you find a transposon insertion within the gene.
What chemical property of the leucine residues thought to form tight ring that prevents the passage of ions within the channel of the acetylcoline receptor suits them for this role.
Imagine you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different compartments. If the genes were expressed in a cell, predict which signal would win out for the following combin..
A neuron with an intracellular Cl- concentration of 50 mM is placed in a solution that contains 100 mM Cl- at 25 degree celcius. The membrane potential of the neuron is -60 mV.
Determine where are the hydrophobic or hydrophilic residues concentrated? Where does your mutation fall relative to these clusters and to the inside or outside of the protein?
Determine how many atp equivalents can be obtained by the complete aaerobic ocidation of 5 molecules of glucose? Suppose 1 complete cycle of the CAC per entry point metabolite
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