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A stock homozygous for three recessive autosomal genes, a, b,and c, not necessarily linked on the same chromosome, ismated to a stock homozygous for their dominant wild-typealleles. F1 females are then backcrossed to males of thehomozygous recessive parental stock and the following cross results are observed:
Phenotype Number Phenotype Number
a bc 42 a b+ 6
+ ++ 48 + +c 4
a ++ 46 a +c 5
+ bc 44 + b+ 5
1. Which of these genes are linked?
2. What is the recombination frequency between the linkedgenes?
Assume you are a graduate student and have been charged with the task to figure out how to differentiate a pluripotent cell into a pancreatic insuin making beta cell.
He speculated that geologic columns would have the most height of 72,000 feet. Using his approach and numbers, compute the approximate age of the earth he came to.
A spotted rabbit, when crossed with a solid-colored rabbit produced all spotted offspring. When these F1 rabbits were crossed among themselves they produced 32 spotted rabbits and 10 solid rabbits.
a number of tumors from inbred animals such as mice and chickens show associated retroviruses. How do you think they affect gene expression in these animals such that it results in cancer?
A person who is lifting weights has taken a bottle of Gatorade into the gym with him. He drinks the Gatorade in between weight machines. Describe what metabolic processes will occur to a molecule of glucose from the drink as he continues to workou..
What kind of modifications protein has to undergo to travel through endomembranous system using secretory vesicles to transport them outside the cell? What is the role of covalent modifications, clevage, etc?
How would you prepare a 250 ml solution, 0.5 M in sodium phosphate buffer at pH of 7.0. You have in the laboratory monobasic sodium phosphate (NaH2PO4) and diabasic sodium phosphate (Na2HPO4). pKa = 7.2.
After contact with a patient spinal fluid a lab technician develop fever nausea and purple lessions on her neck and extremities. A throat culture grew gram negative diplococci. What is genus of the bacteria.
Lysozyme was assayed at bacterial cell wall, = 2.5x10-8 g. The Km for the substrate = 6x10-3g. At the end of one minute 2.5% of the cell wall hydrolysed.
Many of the major waterways in the Tennessee River system are dam-controlled. That means the water level of each section of river may fluctuate significantly at different times of the year. This makes the deployment of Reef Balls in the Tennessee ..
In the process of eukaryotic pre-mRNA splicing, how is the lariat intermediate formed?
The crossover frequency between genes A and D is 40%, between A and C is 20%, between D and E is 10% and between A and E is 30%. What is the sequence of genes on the chromosome?
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