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People with a deficiency in the AIRE protein suffer from a broad spectrum autoimmune disease that involves immune attack against a diverse set of body tissues and organs. Which statement below most accurately provides a mechanistic explanation of this disease? a. These patients have a defect in class II MHC expression which results in an inability to positively select for Th cells. b. These patients do not have a thymus gland and thus are unable to create T lymphocytes. c. These patients suffer from a defect in negative selection of immature B cells. d. These patients suffer from a defect in negative selection of thymocytes.
A young couple went to see a genetic counselor because each had a sibling affected with cystic fibrosis. (Cystic fibrosis is a recessive disease, and neither member of the couple nor any of their four parents is affected.)
Describe b riefly the role of HOX genes in brain development. If a twenty-five year old woman using Accutane to treat acne discovers that she is pregnant, what concerns do you have for the embryo/fetus?
A child is suspected of having an eating disorder. What hormones require to be assessed prior to considering that the situation is primarily psychological?
Estimate which type of protein binds to improperly folded or improperly assembled proteins in the ER, holding them there until proper folding occurs?
The best characterization of apoptosis is: the unwanted, unexpected death of a cell. cell death is a normal consequence of a cell living long enough to eventually be killed by accident.
What would be the genotype and genotype ratio if you crossed wild-type (dominant) female flies with white-eyed (recessive) male flies?
One homozygous strain of silkworm lays white eggs, and another lays black eggs. The F1 offspring of a cross of white and black egg laying silkworms are all found to lay white eggs. Among the F2 progeny, 50 silkworms were found to lay white eggs, 1..
A special Mixture of gases is blended for SCUBA diving that contains 30 percent Oxygen and 70 percent Nitrogen. At atmospheric pressure what is the partial pressure of the oxygen in mmHG.
A cell can use many kinds of organic molecules as fuel for cellular respiration. Distinguish between the use of lipids, carbohydrates and proteins.
A 20 year old garden presents to his family for treatment of what he described as poison ivy. The patient hand and arm appear red and are covered with oozing blisters and crusts. Which of the following best describes the pathogenesis of this skin ..
They have one child. What is the possibility that their child will have the disease. 52 dark moths and 21 light moths were at random recaptured. Which would be the most reasonable assumption.
Determine what sequence of nucleotide pairs in a Drosophila gene will encode the amino acid sequence met-trp-phe-trp-met.
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