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The interaction between bases on different strands of DNA molecules depends somewhat on the identities of neighboring bases. For example, the melting temperature of an oligonucleotide with the sequence GGGGGAAAAA is different than that of GAGAGAGAGA even though both contain the exact same number of G-C and A-T base pairs. (The melting temperature is the temperature at which half of the base pairs are broken between the oligonucleotide and its complementary sequence). Therefore, instead of treating a DNA helix as a string of interactions between base pairs, many thermodynamic algorithms that calculate DNA melting temperatures use the nearest-neighbor model, which treats a DNA helix as a string of interactions between 'neighboring' base pairs. Thus the sequence GGCTGC consists of the nearest neighbors GG, GC, CT, TG and GC. The nearest-neighbor frequencies of a certain double stranded DNA molecule are: AG, 0.15; GT, 0.03; CC, 0.08, and TT, 0.10. In each case the nearest neighbor is written in the 5'?3' direction. What would be the nearest neighbor frequencies of CT, AC, GG and AA?
You have isolated five yeast mutants unable to metabolize galactose. All of the mutants fail to transcribe the GAL2 gene, which encodes the enzyme for the first step in metabolizing galactose.
Using one single color of bead, build a homologous pair of duplicated chromosomes. Each chromosome will have 10 beads with a di%uFB00erent colored centromere in it.
Can viruses evolve? Why or why not? a. No, only their hosts can evolve. b. Yes, their genetic make-up responds to natural selection. c. No, they are not alive. d. Yes, they are able to alter their genetic code directly in response to selection pre..
What are the major adaptations of amphibians, birds, reptiles and mammals? What are the dissimilar types of animals in these groups? Anmiotic egg,plastron, carapace, snake, lizard, turtle, feathers How did jaws evolve.
Describe how the lymphatic system can hinder the spread of cancer. Describe how the lymphatic system may actually aid in the spread of cancer.
A recipe calls for 10 ml of a 25mM stock of EDTA. However, all you have on hand is a five hundred mM stock. How much more concentrated is what you have relative to what the recipe calls for?
A volume of aqueous hydrochloric acid containing 0.500 mol of HCl and 0.100 mol of magnesium metal were combined and reacted to completion. How many liters of hydrogen gas were produced under STP conditions?
In the F2 generation, you find that you have 235 flies displaying the wild type phenotype and 765 flies displaying XYZ phenotype. Which phenotype, Wild type or XYZ, is dominant.
What must the intracellular 3-phosphoglycerate/1, 3-diphosphoglycerate ratio be to make the phosphoglycerate kinase reaction thermodynamically favourable in the direction of 1, 3-diphosphoglycerate synthesis.
Aphids can reproduce sexually and asexually. Females reproduce by themselves and give birth to live females in summer. They also reproduce sexually and lay eggs that survive in summer and eggs that survive in the winter and hatch in the spring.
A nearsighted woman (Nn) with hazel eyes (Hh) marries the man with normal vision and hazel eyes (Hh). Their three children all have blue eyes and normal vision. What is the possibility that their next child will have blue eyes and be nearsight.
In detail compare and contrast photosynthesis and cellular respiration. You should include the types of reactions that occur, the chemical equations of the two processes.
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